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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1 - 6 (6page)
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Non-pulsatile subjective tinnitus is a phantom sound percept without any objective physical sound source. Recent advances in tinnitus research have suggested central rather than peripheral changes as the culprit of tinnitus perception. Moreover, researchers have shown that these central functional changes can be observed not only in the auditory cortex but also in non-auditory regions such as the frontal, parietal, and limbic areas in patients with tinnitus. In this regard, functional neuroimaging modalities such as positron emission tomography (PET), functional magnetic resonance imaging (fMRI), magnetoencephalography (MEG), and quantitative electroencephalography (qEEG) provided researchers with a window into the cerebral cortical activity orchestrating tinnitus. Among these methods, qEEG and MEG are advantageous over PET or fMRI with regard to temporal resolution, while PET and fMRI are advantageous over qEEG or MEG with regard to spatial resolution. In other words, there is no gold standard functional neuroimaging modality in the field of tinnitus, but these four modalities are complementary to one another. In this review article, these four representative functional neuroimaging modalities and their application to tinnitus research will be introduced. Moreover, future direction of functional neuroimaging research on the pathophysiology of tinnitus will be discussed briefly.
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참고문헌 (40)
참고문헌 신청
Weisz N / 2007 / The neural code of auditory phantom perception / J Neurosci 27(6):1479~1484
Schlee W / 2009 / Mapping cortical hubs in tinnitus / BMC Biol 7:80
Worrell GA / 2000 / Localization of the epileptic focus by lowresolution electromagnetic tomography in patients with a lesion demonstrated by MRI / Brain Topogr 12(4):273~282
Mulert C / 2004 / Integration of fMRI and simultaneous EEG: towards a comprehensive understanding of localization and time-course of brain activity in target detection / Neuroimage 22(1):83~94
Vitacco D / 2002 / Correspondence of event-related potential tomography and functional magnetic resonance imaging during language processing / Hum Brain Mapp 17(1):4~12
Schlee W / 2009 / Mapping cortical hubs in tinnitus / BMC Biol 7:80
Worrell GA / 2000 / Localization of the epileptic focus by lowresolution electromagnetic tomography in patients with a lesion demonstrated by MRI / Brain Topogr 12(4):273~282
Mulert C / 2004 / Integration of fMRI and simultaneous EEG: towards a comprehensive understanding of localization and time-course of brain activity in target detection / Neuroimage 22(1):83~94
Vitacco D / 2002 / Correspondence of event-related potential tomography and functional magnetic resonance imaging during language processing / Hum Brain Mapp 17(1):4~12
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