지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제10권 제1호
- 발행연도
- 2017.1
- 수록면
- 91 - 96 (6page)
이용수
초록· 키워드
오류제보하기
Objectives. Budesonide nasal irrigation was introduced recently for postoperative management of patients with chronic rhinosinusitis. The safety and therapeutic effectiveness of this procedure is becoming accepted by many physicians. The objective of this study was to evaluate the efficacy of postoperative steroid irrigation in patients with chronic rhinosinusitis and asthma.
Methods. This prospective study involved 12 chronic rhinosinusitis patients with nasal polyps and asthma who received oral steroid treatment for recurring or worsening disease. The 22-item Sinonasal Outcomes Test (SNOT-22) and Lund-Kennedy endoscopy scores were checked before nasal budesonide irrigation, and 1, 2, 4, and 6 months after irrigation. We also calculated the total amount of oral steroids and inhaled steroids in the 6 months before irrigation and the 6 months after it.
Results. The mean SNOT-22 score improved from 30.8±14.4 before irrigation to 14.2±8.7 after 6 months of irrigation (P=0.030). The endoscopy score also improved from 7.4±4.7 before irrigation to 2.2±2.7 after 6 months (P<0.001). The total amount of oral steroid was decreased from 397.8±97.6 mg over the 6 months before irrigation to 72.7±99.7 mg over the 6 months after irrigation (P<0.001).
Conclusion. Nasal irrigation with budesonide is an effective postoperative treatment for chronic rhinosinusitis with asthma, which recurs frequently, reducing the oral steroid intake.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Adappa ND / 2012 / Nasal irrigation with or without drugs: the evidence / Curr Opin Otolaryngol Head Neck Surg 20 (1) : 53 ~ 57
Bateman ND / 2002 / A study of intranasal distribution of azelastine hydrochloride aqueous nasal spray with different spray techniques / Clin Otolaryngol Allied Sci 27 (5) :
Dijkstra MD / 2004 / Fluticasone propionate aqueous nasal spray does not influence the recurrence rate of chronic rhinosinusitis and nasal polyps 1 year after functional end
Harvey RJ / 2009 / Fluid residuals and drug exposure in nasal irrigation / Otolaryngol Head Neck Surg 141 (6) : 757 ~ 761
Harvey RJ / 2009 / Local drug delivery / Otolaryngol Clin North Am 42 (5) : 829 ~ 845
Bateman ND / 2002 / A study of intranasal distribution of azelastine hydrochloride aqueous nasal spray with different spray techniques / Clin Otolaryngol Allied Sci 27 (5) :
Dijkstra MD / 2004 / Fluticasone propionate aqueous nasal spray does not influence the recurrence rate of chronic rhinosinusitis and nasal polyps 1 year after functional end
Harvey RJ / 2009 / Fluid residuals and drug exposure in nasal irrigation / Otolaryngol Head Neck Surg 141 (6) : 757 ~ 761
Harvey RJ / 2009 / Local drug delivery / Otolaryngol Clin North Am 42 (5) : 829 ~ 845
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