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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제14권 제1호
- 발행연도
- 2010.1
- 수록면
- 31 - 40 (10page)
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초록· 키워드
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Purpose : To compare the relative values of various fast breath-hold imaging sequences for superparamagnetic iron-oxide (SPIO)-enhanced hepatic MRI for the assessment of solid focal lesions with a 3T MRI unit.
Materials and Methods : 102 consecutive patients with one or more solid malignant hepatic lesions were evaluated by spoiled gradient echo (GRE) sequences with three different echo times (2.4 msec [GRE_2.4], 5.8 msec [GRE_5.8], and 10 msec [GRE_10]) for T2*-weighted imaging in addition to T2-weighted turbo spin echo (TSE) sequence following intravenous SPIO injection. Image qualities of the hepatic contour, vascular landmarks and artifacts were rated by two independent readers using a four-point scale. For quantitative analysis, contrast-to-noise ratio (CNR) was measured in 170 solid focal lesions larger than 1 cm (107 hepatocellular carcinomas, nine cholangiocarcinomas and 54 metastases).
Results : GRE_5.8 showed the highest mean points for hepatic contour, vascular anatomy and imaging artifact presence among all of the subjected sequences (p<0.001) and was comparable (p=0.414) with GRE_10 with regard to lesion conspicuity. The mean CNRs were significantly higher (p<0.001) in the following order: GRE_10 (24.4±14.5), GRE_5.8 (14.8±9.4), TSE (9.7±6.3), and GRE_2.4 (7.9±6.4). The mean CNRs of CCCs and metastases were higher than those of HCCs for all imaging sequences (p<0.05).
Conclusion : Regarding overall performances, GRE using a moderate echo time of 5.8 msec can provide the most reliable data among the various fast breath-hold SPIOenhanced hepatic MRI sequences at 3T unit despite the lower CNR of GRE_5.8 compared to that of GRE_10.
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참고문헌 (22)
참고문헌 신청
Bellin MF / 1994 / Liver metastases: safety and Efficacy of detection with superparamagnetic iron oxide in MR imaging / Radiology 193 : 657 ~ 663
Bottomley PA / 1984 / A review of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1-100 MHz: dependence on tissue type, NMR frequency, temperature
Chang JM / 2006 / Superparamagnetic iron oxide-enhanced liver magnetic resonance imaging-comparison of 1.5T and 3.0T imaging for detection of focal malignant liver lesions /
Hahn PF / 1990 / Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors / Radiology 174 : 361 ~ 366
Kim MJ / 2006 / Optimal TE for SPIOenhanced gradient-recalled echo MRI for the detection of focal hepatic lesions / AJR Am J Roentgenol 187 : W255 ~ W266
Bottomley PA / 1984 / A review of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1-100 MHz: dependence on tissue type, NMR frequency, temperature
Chang JM / 2006 / Superparamagnetic iron oxide-enhanced liver magnetic resonance imaging-comparison of 1.5T and 3.0T imaging for detection of focal malignant liver lesions /
Hahn PF / 1990 / Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors / Radiology 174 : 361 ~ 366
Kim MJ / 2006 / Optimal TE for SPIOenhanced gradient-recalled echo MRI for the detection of focal hepatic lesions / AJR Am J Roentgenol 187 : W255 ~ W266
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