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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 267 - 271 (5page)
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초록· 키워드
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The bone is a common site for metastasis in hepatocellular carcinoma (HCC). However, bone marrow metastasis from HCC is rarely reported, and its frequency is unclear. Here we report a rare case of bone marrow metastasis that presented as bicytopenia originating from HCC without bone metastasis. A 58-year-old man was admitted for investigation of a liver mass with extensive lymph node enlargement that was detected when examining his general weakness and weight loss. Laboratory findings revealed anemia, thrombocytopenia, mild elevated liver enzymes, normal prothrombin time percentage and high levels of tumor markers (α-fetoprotein and des-γ-carboxyprothrombin). Abdominal computed tomography showed multiple enhanced masses in the liver and multiple enlarged lymph nodes in the abdomen. A bone marrow biopsy revealed only a few normal hematopoietic cells and abundant tumor cells. Despite its rarity, bone marrow metastasis should always be suspected in HCC patients even if accompanied by cirrhosis.
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등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Arii S / 2000 / Results of surgical and nonsurgical treatment for small-sized hepatocellular carcinomas: a retrospective and nationwide survey in Japan. The Liver Cancer Study Group of Japan / Hepatology 32:1224~1229
Shiina S / 1993 / Percutaneous ethanol injection therapy for hepatocellular carcinoma: results in 146 patients / AJR Am J Roentgenol 160:1023~1028
Llovet JM / 2002 / Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial / Lancet 359:1734~1739
Shiina S / 2005 / A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma / Gastroenterology 129:122~130
Mazzaferro V / 1996 / Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis / N Engl J Med 334:693~699
Shiina S / 1993 / Percutaneous ethanol injection therapy for hepatocellular carcinoma: results in 146 patients / AJR Am J Roentgenol 160:1023~1028
Llovet JM / 2002 / Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial / Lancet 359:1734~1739
Shiina S / 2005 / A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma / Gastroenterology 129:122~130
Mazzaferro V / 1996 / Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis / N Engl J Med 334:693~699
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