지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 355 - 361 (7page)
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초록· 키워드
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Purpose: The purpose of the present study was to identify more useful parameters for predicting behaviors of multifocal papillary thyroid carcinoma (PTC). Materials and Methods: We investigated dominant tumor diameter (TD), total tumor diameter(TTD), and total surface area (TSA) in tumors from 588 patients and evaluated their usefulness as parameters for assessment of tumor behaviors in multifocal PTCs. Results: In 588 PTCs, tumor multifocality was found in 179 PTCs (30.4%). Multifocal tumors were significantly associated with extrathyroidal extension, lymph node metastasis, and higher tumor stage grouping (p<0.001, p<0.001, and p<0.001, respectively). The rates of nodal metastasis increased with greater TSA and TTD in PTCs. Multifocal papillary thyroid microcarcinomas (mPMCs) with TSA >3.14 cm2 had higher rates of nodal metastasis than mPMCs with TSA ≤3.14 cm2 (p=0.038); however, there was no significant difference between mPMCs with TTD >1.0 cm and with TTD ≤1.0 cm (p=0.325). In addition, nodal metastasis was more frequent in mPMCs with TSA >3.14 cm2 than in unifocal papillary thyroid microcarcinomas(uPMCs) (TD ≤1.0 cm) (p=0.002), but not overt unifocal PTCs (TD >1.0 cm) (p=0.244). Conclusion: Our results suggest that mPMCs with TSA >3.14 cm2 show more aggressive behavior than uPMCs and mPMCs with TSA ≤3.14 cm2. TSA could be useful in distinguishing aggressive mPMCs from favorable cases.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer / 2009 / Revised American Thyroid Association management guideli
Andea AA / 2004 / Correlation of tumor volume and surface area with lymph node status in patients with multifocal/multicentric breast carcinoma / Cancer 100 : 20 ~ 27
Chow SM / 2003 / Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality / Cancer 98 : 31 ~ 40
Ciuffreda L / 2011 / Our experience on surgical treatment of papillary thyroid microcarcinoma / G Chir 32 : 41 ~ 44
Connor MP / 2011 / Variables predictive of bilateral occult papillary microcarcinoma following total thyroidectomy / Otolaryngol Head Neck Surg 144 : 210 ~ 215
Andea AA / 2004 / Correlation of tumor volume and surface area with lymph node status in patients with multifocal/multicentric breast carcinoma / Cancer 100 : 20 ~ 27
Chow SM / 2003 / Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality / Cancer 98 : 31 ~ 40
Ciuffreda L / 2011 / Our experience on surgical treatment of papillary thyroid microcarcinoma / G Chir 32 : 41 ~ 44
Connor MP / 2011 / Variables predictive of bilateral occult papillary microcarcinoma following total thyroidectomy / Otolaryngol Head Neck Surg 144 : 210 ~ 215
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