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논문 기본 정보

자료유형
학술저널
저자정보
김민주 (서울대학교병원) 문재훈 (분당서울대학교병원) 이은경 (국립암센터) 송영신 (서울특별시보라매병원) 정경연 (을지대학교) 이지예 (서울대학교 의과대학 서울대학교병원 영상의학과) 김지훈 (서울대학교병원) 김경식 (Deparments of Preventive Medicine, Seoul National University College of Medicine, Korea) Sue K. Park (Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea) 박영주 (서울대학교)
저널정보
대한내분비학회 Endocrinology and Metabolism Endocrinology and Metabolism Vol.39 No.1
발행연도
2024.2
수록면
47 - 60 (14page)
DOI
https://doi.org/10.3803/EnM.2024.1937

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The indolent nature and favorable outcomes associated with papillary thyroid microcarcinoma have prompted numerous prospective studies on active surveillance (AS) and its adoption as an alternative to immediate surgery in managing low-risk thyroid cancer. This article reviews the current status of AS, as outlined in various international practice guidelines. AS is typically recommended for tumors that measure 1 cm or less in diameter and do not exhibit aggressive subtypes on cytology, extrathyroidal extension, lymph node metastasis, or distant metastasis. To determine the most appropriate candidates for AS, factors such as tumor size, location, multiplicity, and ultrasound findings are considered, along with patient characteristics like medical condition, age, and family history. Moreover, shared decision-making, which includes patient-reported outcomes such as quality of life and cost-effectiveness, is essential. During AS, patients undergo regular ultrasound examinations to monitor for signs of disease progression, including tumor growth, extrathyroidal extension, or lymph node metastasis. In conclusion, while AS is a feasible and reliable approach for managing lowrisk thyroid cancer, it requires careful patient selection, effective communication for shared decision-making, standardized follow-up protocols, and a clear definition of disease progression.

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