지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 1,488 - 1,493 (6page)
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초록· 키워드
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Purpose: To assess the ability of a mechanical in-exsufflator (MI-E), either alone or in combination with manual thrust, to augment cough in patients with neuromuscular disease (NMD) and respiratory muscle dysfunction.
Materials and Methods: For this randomized crossover single-center controlled trial, patients with noninvasive ventilator-dependentNMD were recruited. The primary outcome was peak cough flow (PCF), which was measured in each patient after a cough that was unassisted, manually assisted following a maximum insufflation capacity (MIC) maneuver, assisted by MI-E, or assistedby manual thrust plus MI-E. The cough augmentation techniques were provided in random order. PCF was measured usinga new device, the Cough Aid.
Results: All 40 enrolled participants (37 males, three females; average age, 20.9±7.2 years) completed the study. The mean (standarddeviation) PCFs in the unassisted, manually assisted following an MIC maneuver, MI-E-assisted, and manual thrust plus MI-E-assisted conditions were 95.7 (40.5), 155.9 (53.1), 177.2 (33.9), and 202.4 (46.6) L/min, respectively. All three interventions significantly improved PCF. However, manual assistance following an MIC maneuver was significantly less effective than MI-E alone. Manual thrust plus MI-E was significantly more effective than both of these interventions.
Conclusion: In patients with NMD and respiratory muscle dysfunction, MI-E alone was more effective than manual assistance following an MIC maneuver. However, MI-E used in conjunction with manual thrust improved PCF even further.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
강성웅 / 2005 / Assisted Cough and Pulmonary Compliance in Patients with Duchenne Muscular Dystrophy / Yonsei Medical Journal 46(2):233~238
Finder JD / 2010 / Airway clearance modalities in neuromuscular disease / Paediatr Respir Rev 11:31~34
Homnick DN / 2007 / Mechanical insufflation-exsufflation for airway mucus clearance / Respir Care 52:1296~1305
Bach JR / 1993 / Mechanical insufflation-exsufflation. Comparison of peak expiratory flows with manually assisted and unassisted coughing techniques / Chest 104:1553~1562
Morrow B / 2013 / Mechanical insuffation-exsuffation for people with neuromuscular disorders / Cochrane Database Syst Rev (12):CD010044
Finder JD / 2010 / Airway clearance modalities in neuromuscular disease / Paediatr Respir Rev 11:31~34
Homnick DN / 2007 / Mechanical insufflation-exsufflation for airway mucus clearance / Respir Care 52:1296~1305
Bach JR / 1993 / Mechanical insufflation-exsufflation. Comparison of peak expiratory flows with manually assisted and unassisted coughing techniques / Chest 104:1553~1562
Morrow B / 2013 / Mechanical insuffation-exsuffation for people with neuromuscular disorders / Cochrane Database Syst Rev (12):CD010044
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