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연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제56권 제5호
발행연도
2015.1
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1,352 - 1,358 (7page)

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Purpose: To show the results of an audit of screening breast ultrasound (US) in women with negative mammography in a single institution and to analyze US-detected cancers within a year and interval cancers. Materials and Methods: During the year of 2006, 1974 women with negative mammography were screened with US in our screening center, and 1727 among them had pathologic results or any follow up breast examinations more than a year. We analyzedthe distribution of Breast Imaging Reporting and Data System (BI-RADS) category and the performance outcome through follow up. Results: Among 1727 women (age, 30–76 years, median 49.5 years), 1349 women (78.1%) showed dense breasts on mammography,762 (44.1%) had previous breast US, and 25 women (1.4%) had a personal history of breast cancers. Test negatives were 94.2% (1.627/1727) [BI-RADS category 1 in 885 (51.2%), 2 in 742 (43.0%)]. The recall rate (=BI-RADS category 3, 4, 5) was 5.8%. Eight cancers were additionally detected with US (yield, 4.6 per 1000). The sensitivity, specificity, and positive predictive value (PPV1, PPV2) were 88.9%, 94.6%, 8.0%, and 28.0%, respectively. Eight of nine true positive cancers were stage I or in-situ cancers. One interval cancer was stage I cancer from BI-RADS category 2. Conclusion: Screening US detected 4.6 additional cancers among 1000. The recall rate was 5.8%, which is in lower bound of acceptablerange of mammography (5–12%), according to American College of Radiology standard.

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