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학술저널
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연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제59권 제7호
발행연도
2018.1
수록면
887 - 896 (10page)

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Purpose: To compare the diagnostic abilities of swept-source optical coherence tomography (OCT) [Deep Range Imaging OCT-1(DRI-OCT)] and spectral-domain OCT (Cirrus HD-OCT) for glaucoma in Korean adults. Materials and Methods: This retrospective study involved measuring peripapillary retinal nerve fiber layer (PP-RNFL) thickness,full macular thickness, and ganglion cell-inner plexiform layer (GC-IPL) thickness on two different OCT systems. We used threedimensionaloptic disc scanning of DRI-OCT and included 12 clock-hour sectors for measurement of the PP-RNFL. Areas underreceiver operating characteristic curves (AUCs) were calculated and compared to determine how well each system could distinguishcontrol and glaucomatous patients. Results: Ninety-one healthy and 58 glaucomatous eyes were included. Both systems could clearly distinguish between controleyes and eyes with moderate to severe glaucoma. Among all sectors, the AUC values of areas associated with glaucoma were >0.7for both OCTs. The PP-RNFL sector of highest AUC value on both OCTs was the inferior sector of the clock-hour map (0.968 and0.959 in DRI-OCT and Cirrus HD-OCT, respectively). Among macular thickness sectors, AUC values were highest on both OCTs forthe outer inferior sector (0.859 and 0.853 in DRI-OCT and Cirrus HD-OCT, respectively). The GC-IPL also provided high diagnosticvalues (DRI-OCT and Cirrus HD-OCT were the best in the average and inferior sectors, respectively). Conclusion: Although the two OCT systems provided different thickness measurements, DRI-OCT exhibited as good, if not better,diagnostic ability for glaucoma as Cirrus HD-OCT in Korean adults.

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