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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 290 - 295 (6page)
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초록· 키워드
오류제보하기
Purpose: To compare the 1-year outcomes of a durable polymer Zotarolimus-eluting stent (ZES) versus a biodegradable polymer Biolimus-eluting stent (BES) in patients undergoing percutaneous coronary intervention.
Materials and Methods: A total of 2083 patients from 2 different registries, 1125 treated with BES in NOBORI registry and 858 receivedZES in CONSTANT registry were included in this study. Clinical outcomes were compared with the use of propensity score matching (PSM). The primary endpoint was a composite of major adverse cardiovascular and cerebrovascular events (MACCEs) includingcardiac death, myocardial infarction, clinically driven target lesion revascularization and stroke. Secondary end points were individual components of MACCEs as well as the incidence of stent thrombosis at 1-year follow-up.
Results: After PSM, 699 matched pairs of patients (n=1398) showed no significant difference between BES and ZES in the risk of composite MACCEs at 1 year (2.6% vs. 1.7%; p=0.36). Cardiac death was not statistically different between groups (0.7% vs. 0.4%, p=0.73). Target lesion revascularization rate was also similar between BES and ZES (1.1% vs. 0.7%, p=0.579). Non-Q wave myocardial infarction, as well as target-vessel revascularization rate, was similar between the two groups (0.14% for BES and 0.72% for ZES). Both stent types were excellent with no cases of stent thrombosis and rate of Q wave myocardial infarction reported during the follow-up period.
Conclusion: In this cohort of patients treated with BES or ZES, the rate of MACCEs at 1 year was low and significantly not different between both groups.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Austin PC / 2011 / An introduction to propensity score methods for reducing the effects of confounding in observational studies / Multivariate Behav Res 46 : 399 ~ 424
Bangalore S / 2012 / Short- and long-term outcomes with drug-eluting and baremetal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-u
Camenzind E / 2007 / Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern / Circulation 115 : 1440 ~ 1455
Christiansen EH / 2013 / Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutane
Cutlip DE / 2007 / Clinical end points in coronary stent trials: a case for standardized definitions / Circulation 115 : 2344 ~ 2351
Bangalore S / 2012 / Short- and long-term outcomes with drug-eluting and baremetal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-u
Camenzind E / 2007 / Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern / Circulation 115 : 1440 ~ 1455
Christiansen EH / 2013 / Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutane
Cutlip DE / 2007 / Clinical end points in coronary stent trials: a case for standardized definitions / Circulation 115 : 2344 ~ 2351
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