지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치매학회 Dementia and Neurocognitive Disorders(대한치매학회지) Dementia and Neurocognitive Disorders(대한치매학회지) 제15권 제2호
- 발행연도
- 2016.1
- 수록면
- 37 - 42 (6page)
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초록· 키워드
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Background and PurposeAlthough depression is a common psychiatric symptom in Alzheimer’s disease (AD), there has not been a lot of research on neuropsychological characteristics of this symptom. To determine the characteristic neuropsychological deficit in patients with depression compared to patients without depression, this study compared each neuropsychological test between AD patients with depression and without depression.
MethodsPsychotropic-naïve (drug-naïve) early stage [Clinical Dementia Rating Scale (CDR)=0.5 or CDR=1] probable AD patients with depression (n=77) and without depression (n=179) were assessed with the Seoul Neuropsychological Screening Battery, which includes measures of memory, intelligence, and executive functioning.
ResultsAD patients with depression had lower scores on the digit forward, digit backward, calculation, and Color Word Stroop Test tests compared to AD patients without depression.
ConclusionsOur study showed that AD patients with depression have disproportionate cognitive deficit, suggesting frontal (especially in the left dorsolateral), left hemisphere and left parietal dysfunction. Considering the neuropsychological differences between AD patients with depression and without depression, depression may have specific anatomic substrates.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Mathews A / 2005 / Cognitive vulnerability to emotional disorders / Annu Rev Clin Psychol 1:167~195
Rose EJ / 2006 / Pattern of impaired working memory during major depression / J Affect Disord 90:149~161
van Reekum R / 1999 / Late-life depression as a possible predictor of dementia : cross-sectional and short-term follow-up results / Am J Geriatr Psychiatry 7:151~159
Rovner BW / 1989 / Depression and Alzheimer’s disease / Am J Psychiatry 146:350~353
Rubin EH / 1991 / The influence of major depression on clinical and psychometric assessment of senile dementia of the Alzheimer type / Am J Psychiatry 148:1164~1171
Rose EJ / 2006 / Pattern of impaired working memory during major depression / J Affect Disord 90:149~161
van Reekum R / 1999 / Late-life depression as a possible predictor of dementia : cross-sectional and short-term follow-up results / Am J Geriatr Psychiatry 7:151~159
Rovner BW / 1989 / Depression and Alzheimer’s disease / Am J Psychiatry 146:350~353
Rubin EH / 1991 / The influence of major depression on clinical and psychometric assessment of senile dementia of the Alzheimer type / Am J Psychiatry 148:1164~1171
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