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자료유형
학술저널
저자정보
저널정보
대한약침학회 Journal of Pharmacopuncture Journal of Pharmacopuncture 제2권 제1호
발행연도
1999.1
수록면
135 - 152 (18page)

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To investigate effects of Taraxaci herbal-acupuncture on Adjuvant Arthritis in rats, the edema rate, the number of WBC, the quantity of total protein, albumin and globulin in the blood serum and histological test of the muscular tissue were measured in the arthritis part. 1. After elicitating arthritis of Sprague Dawely(SD) rats by injection of Freund's complets adjuvant for 2 weeks, saline was injected for the Exp. I group and Taraxaci herbal-acupuncture was injected for the Exp. II group during 30days. Selected point was ST35 in both the groups. And then the volume of the paw were checked. The volume of paw was 0.84±0.14mm in the Exp. I group and 0.38±0.17mm in the Exp. II group, the swelling of the paw was restricted significantly in the Exp. II group(p<0.05) 2. The number of WBC was 10.34±0.14(103/ml) in the normal group and 37.47±5.46(103/ml) in the Exp. I group. It was 20.39±4.23(103/ml) in the Exp. II group. This fact showed that the group Exp. II was more effective than the Exp. I group in the treatment of arthritis(p<0.05) 3. The content of the total protein in the blood serum was 6.14±0.43g/dl in the normal group, 7.95±0.94g/dl in the Exp. I group, and 6.38±1.75g/dl in the Exp. II group. This fact showed that the group Exp. II was more effective than the Exp. I group in the treatment of arthritis(p<0.05) 4. The contents of albumin in the blood serum was 2.94±0.13g/dl in the normal group, 2.01±0.48g/dl in the Exp. I group. and 2.71±0.34g/dl in the Exp. II group. This fact showed that the group Exp. II was more effective than the Exp. I group in the treatment of arthritis(p<0.05) 5. The contents of globulin in the blood serum was 3.19±0.48g/dl in the normal group, 4.70±1.26g/dl in the Exp. I group. and 3.67±0.56g/dl in the Exp. II group. There was no significance in the serum globulin between Exp. II group and Exp. I group from the stastical analysis 6. In histological finding, because of severe inflammatory reaction, remarkably irregular tissue and large amount of inflammatory cells were found in the Exp. I group. But the Exp. II group showed small amount of inflammatory cells, the refrained inflammatory state and even recovering state. From these results, it is showed Taraxaci herbal-acupuncture refrain inflammatory reaction and muscular tissue necrosis in SD rats paw were induced by Freund's complete adjuvant

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