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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 201 - 206 (6page)
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Objectives: The aim of this study was to investigate the effects of Cassia acutifolia on the obesity and the glucose levels in a rat model of obesity and diabetes.
Methods: By random selection, 36 Wistar male rats were divided in two control groups, the positive and the negative control groups, and into four experimental groups receiving different infusions of Cassia acutifolia in water ad libitum.
Results: The results revealed a statistically significant anti-obesogenic effect (P = 0.02), although this was not considered clinically significant. Additionally, Cassia acutifolia lowered the glucose levels by 30 mg/dL to 90 mg/dL (P = 0.05). However, we observed adverse effects in the liver, a two-fold increase in transaminase levels (P = 0.002), and in the kidneys, decreased creatinine levels (P = 0.001), and these adverse effects had no viable explanation.
Conclusion: Cassia acutifolia has anti-hyperglycemic effects in obese diabetic rats. However, Cassia acutifolia also has adverse effects, so it should not be administered to patients.
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참고문헌 (8)
참고문헌 신청
/ / Organizacion Mundial de la Salud
/ / Organizacion Mundial de la Salud: Que es diabtes
Annadurai T / 2012 / Antihyperglycemic and antioxidant effects of a flavanone, naringenin, in streptozotocin-nicotinamide-induced experimental diabetic rats / J Physiol Bioch
Garcia-Cobian TA / 2015 / Efecto de Azadirachta Indica sobre insulina y peptido c en un modelo de ratas obesas / XVII Congreso Internacional de Avances en Medicina
Gutierrez JP / 2012 / Encuesta nacional de salud y nutricion 2012. resultados Nacionales / Instituto Nacional de Salud Publica (MX) : 200 ~
/ / Organizacion Mundial de la Salud: Que es diabtes
Annadurai T / 2012 / Antihyperglycemic and antioxidant effects of a flavanone, naringenin, in streptozotocin-nicotinamide-induced experimental diabetic rats / J Physiol Bioch
Garcia-Cobian TA / 2015 / Efecto de Azadirachta Indica sobre insulina y peptido c en un modelo de ratas obesas / XVII Congreso Internacional de Avances en Medicina
Gutierrez JP / 2012 / Encuesta nacional de salud y nutricion 2012. resultados Nacionales / Instituto Nacional de Salud Publica (MX) : 200 ~
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