수술 전 갑상선 유두상암의 경부 림프절 전이 진단에 있어 18F FDG PET-CT의 의의

유영범; 김수란; 강현종; 박경식; 백남선

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자료유형: 학술저널

저자정보: 유영범 김수란 강현종 박경식 백남선

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제10권 제4호

발행연도: 2010.1

수록면: 235 - 239 (5page)

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Purpose: To compare the diagnostic accuracy of US/CT with US/CT/18F-FDG PET-CT in the diagnosis of cervical lymph nodes metastasis in papillary thyroid carcinoma. Methods: From July 2008 to May 2010, 36 patients with papillary thyroid carcinoma, confirmed by aspiration cytology analysis, underwent neck US, neck CT and 18F-FDG PET-CT preoperatively. The sensitivity, specificity and diagnostic accuracy of the US/CT, US/CT/PET-CT was analyzed according to lymph node level (all: levels I∼VI, central: level VI, lateral: levels I∼V). Results: At all lymph nodes group (level I∼VI), US/CT/ PET-CT showed a sensitivity of 66.6%, a specificity of 61.9% and a diagnostic accuracy of 63.8%. The corresponding values for US/CT were 60.0%, 85.7%, 75.0% respectively. Considering the central cervical nodes group (level VI), US/CT/PET-CT showed a sensitivity of 57.1%, a specificity of 68.1%, and a diagnostic accuracy of 63.8%. The corresponding values of US/CT were 57.1%, 90.9%, 77.7% respectively. Considering the lateral cervical nodes group (level I∼V), US/CT/PET-CT showed a sensitivity of 100%, a specificity of 84.3%, and a diagnostic accuracy of 86.1%. The corresponding values of US/CT were 75.0%, 84.3%, 83.3% respectively. The diagnostic results of US/ CT, US/CT/PET-CT in initial evaluation of the cervical nodes metastasis did not differ significantly. Conclusion: Our preliminary results suggest that additional PET-CT evaluation in US/CT does not provide statistically significant benefit for initial diagnosis of cervical lymph nodes metastasis in papillary thyroid carcinoma. (Korean J Endocrine Surg 2010;10:235-239)

#갑상선 유두상암 #경부 림프절 전이 #Papillary thyroid carcinoma #Cervical lymph nodes metastasis #18F FDG PET-CT #18F FDG PET-CT

참고문헌 (15)

참고문헌 신청

Dietlein M / 1997 / Fluorine-18 fluorodeoxyglucose positron emission tomography and iodine-131 whole-body scintigraphy in the follow-up of differentiated thyroid cnacer / Eu

Hundahl SA / 1998 / A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S. 1985-1995 / Cancer 83 : 2638 ~ 2648

Ito Y / 2005 / Ultra-sonographically and anatomopathologically detectable node metastases in the lateral compartment as indicators of worse relapse-free survival in patients

KimEH / 2008 / Preoperative diagnosis of cervical metastatic lymph nodes in papillary thyroid carcinoma: Comparison of ultrasound, computed tomography, and combined ultrasou

Kouvaraki MA / 2003 / Role of preoperative ultrasonography in the surgical management of patients with thyroid cancer / Surgery 134 : 946 ~ 954

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