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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 191 - 198 (8page)
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Purpose: The purpose of this study was to assess the presence of contralateral occult malignant foci (OMF) among patients who confined unilateral papillary thyroid carcinomas (PTCs). Methods: From January 2010 to December 2012, we retrospectively evaluated 714 patients who received total thyroidectomy with central lymph node (LN) dissection after being diagnosed as having unilaterally confined PTC. By dividing the patients into 2 groups according to the presence or absence of contralateral OMF, the relationship between OMF and clinicopathological factors such as age, sex, tumor size, multifocality, chronic lymphocytic/Hashimoto's thyroiditis, contralateral lobe benign nodule, extrathyroidal extension (ETE), and central LN metastasis. Results: When the patients were subdivided based on primary tumor size, OMF in the contralateral lobe were more frequently found as the tumor sizes increased, with statistical significance (P=0.012). In the patients with multifocal thyroid cancer in the lobe that had primary tumor, OMF was observed in the other lobe regardless of the number of primary malignant nodules, and the difference was statistically significant (P=0.001). Conclusion: The primary tumor size or multifocality is a risk factor that can predict the presence of contralateral lobe occult cancers. We suggest that patient needs to carefully observe the remaining contralateral lobe, taking into consideration the size and multifocality of the primary tumor, when performing unilateral thyroid lobectomy.
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참고문헌 (46)
참고문헌 신청
Kim EK / 2002 / New sonographic criteria for recommending fine-needle aspiration biopsy of nonpalpable solid nodules of the thyroid / AJR Am J Roentgenol 178:687~691
Hong YJ / 2010 / Positive predictive value of sonographic features of solid thyroid nodule / Clin Imaging 34:127~133
Siegel R / 2014 / Cancer statistics, 2014 / CA Cancer J Clin 64:9~29
Markovina S / 2014 / Treatment approach, surveillance, and outcome of well-differentiated thyroid cancer in childhood and adolescence / Thyroid 24:1121~1126
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules / 2009 / Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19:1167~1214
Hong YJ / 2010 / Positive predictive value of sonographic features of solid thyroid nodule / Clin Imaging 34:127~133
Siegel R / 2014 / Cancer statistics, 2014 / CA Cancer J Clin 64:9~29
Markovina S / 2014 / Treatment approach, surveillance, and outcome of well-differentiated thyroid cancer in childhood and adolescence / Thyroid 24:1121~1126
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules / 2009 / Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19:1167~1214
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Bilateral Papillary Thyroid Cancer Increases the Risk of Lymph Node Metastasis Compared with Unilateral Multifocal Papillary Thyroid Cancer
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