지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.6
- 수록면
- 33 - 38 (6page)
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초록· 키워드
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Purpose: The extent of surgery necessary in patients with unilateral papillary thyroid carcinoma (PTC) on preoperative radiologic imaging is still in doubt. In this study, we aimed to define risk factors that could be indicators for malignant nodules in the contralateral thyroid lobe.
Methods: We included 438 patients who underwent total thyroidectomy between January 2011 and December 2014 at our institution. In this study, patients were divided into two groups according to the presence of contralateral occult carcinoma identified by postoperative pathological examination. We analyzed the clinicopathologic factors including characteristics of coexistent nodules in the contralateral lobe based on preoperative radiological imaging.
Results: A total of 96 patients (21.9%) had PTC in the contralateral lobe. There were no significant differences between patients with or without contralateral occult carcinoma with respect to gender, age, primary tumor size, central lymph node metastasis, extrathyroidal extension and stage. The presence of Hashimoto’s thyroiditis was an independent predictive factor for contralateral occult carcinoma (P=0.01).
Conclusion: A risk factor for contralateral occult carcinoma in unilateral PTC patients is Hashimoto’s thyroiditis. Therefore, more caution is needed when determining optimal surgical methods for PTC patients with Hashimoto’s thyroiditis.
Methods: We included 438 patients who underwent total thyroidectomy between January 2011 and December 2014 at our institution. In this study, patients were divided into two groups according to the presence of contralateral occult carcinoma identified by postoperative pathological examination. We analyzed the clinicopathologic factors including characteristics of coexistent nodules in the contralateral lobe based on preoperative radiological imaging.
Results: A total of 96 patients (21.9%) had PTC in the contralateral lobe. There were no significant differences between patients with or without contralateral occult carcinoma with respect to gender, age, primary tumor size, central lymph node metastasis, extrathyroidal extension and stage. The presence of Hashimoto’s thyroiditis was an independent predictive factor for contralateral occult carcinoma (P=0.01).
Conclusion: A risk factor for contralateral occult carcinoma in unilateral PTC patients is Hashimoto’s thyroiditis. Therefore, more caution is needed when determining optimal surgical methods for PTC patients with Hashimoto’s thyroiditis.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (27)
참고문헌 신청
Pitt SC / 2009 / Contralateral papillary thyroid cancer : does size matter / Am J Surg 197:342~347
Mazeh H / 2011 / Multifocality in well-differentiated thyroid carcinomas calls for total thyroidectomy / Am J Surg 201:770~775
Pasieka JL / 1992 / The incidence of bilateral well-differentiated thyroid cancer found at completion thyroidectomy / World J Surg 16:711~717
Haugen BR / 2016 / 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer : the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer / Thyroid 26:1~133
소윤경 / 2015 / Multifocality and Bilaterality of Papillary Thyroid Microcarcinoma / Clinical and Experimental Otorhinolaryngology 8(2):174~178
Mazeh H / 2011 / Multifocality in well-differentiated thyroid carcinomas calls for total thyroidectomy / Am J Surg 201:770~775
Pasieka JL / 1992 / The incidence of bilateral well-differentiated thyroid cancer found at completion thyroidectomy / World J Surg 16:711~717
Haugen BR / 2016 / 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer : the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer / Thyroid 26:1~133
소윤경 / 2015 / Multifocality and Bilaterality of Papillary Thyroid Microcarcinoma / Clinical and Experimental Otorhinolaryngology 8(2):174~178
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UCI(KEPA) : I410-ECN-0101-2020-514-000882478