지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: The aim of this study was to evaluate the agreement between the fracture-risk assessment tool (FRAX®)-based intervention strategy in Turkey and the recommendations published in the Healthcare Practices Statement (HPS). Methods: This descriptive cross-sectional study included individuals aged 40 to 90 years who were previously diagnosed as having osteoporosis but had not received any treatment. The intervention thresholds recommended by the National Osteoporosis Foundation for treatment were used. The criteria necessary for the start of administration of pharmacological agents in osteoporosis treatment were evaluated on the basis of the HPS guidelines. Results: Of the 1,255 patients evaluated, 161 (12.8%) were male and 1,094 (87.2%) were female. In the evaluation, according to HPS, treatment was recommended for 783 patients (62.4%; HPS+) and not recommended for 472 (37.6%; HPS-). Of the 783 HPS+ patients, 391 (49.9%) were FRAX+, and of the 472 HPS- patients, 449 (95.1%) were FRAX−. A statistically significant difference was observed between the treatment recommendations of HPS and FRAX® (P<0.001). In the age group of 75 to 90 years, excellent agreement was found between the two strategies (Gwet’s agreement coefficient 1=0.94). As age increased, the agreement between the two treatment strategies also increased. Conclusions: The FRAX® model has different treatment recommendation rates from the HPS. The agreement between the two is at a minimal level. However, as age increased, so did the agreement between the FRAX® and the HPS treatment recommendations. In the recommendation to start pharmacological treatment primarily based on age, non-medical interventions that preserve bone density should be evaluated.
목차
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참고문헌 (30)
참고문헌 신청
El-Hajj Fuleihan G / 2017 / Worldwide fracture prediction / J Clin Densitom 20:397~424
Cosman F / 2014 / Clinician’s guide to prevention and treatment of osteoporosis / Osteoporos Int 25:2359~2381
Compston J / 2017 / UK clinical guideline for the prevention and treatment of osteoporosis / Arch Osteoporos 12:43
Kanis JA / 2013 / European guidance for the diagnosis and management of osteoporosis in postmenopausal women / Osteoporos Int 24:23~57
Lekamwasam S / 2013 / Sri Lankan FRAX model and country-specific intervention thresholds / Arch Osteoporos 8:148
Cosman F / 2014 / Clinician’s guide to prevention and treatment of osteoporosis / Osteoporos Int 25:2359~2381
Compston J / 2017 / UK clinical guideline for the prevention and treatment of osteoporosis / Arch Osteoporos 12:43
Kanis JA / 2013 / European guidance for the diagnosis and management of osteoporosis in postmenopausal women / Osteoporos Int 24:23~57
Lekamwasam S / 2013 / Sri Lankan FRAX model and country-specific intervention thresholds / Arch Osteoporos 8:148
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