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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 517 - 524 (8page)
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초록· 키워드
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In this study, the essential oil from lotus flower extract,
including petals and stamens, was assessed with regard
to its effects on melanogenesis in human melanocytes.
The lotus flower essential oil was shown to
stimulate melanin synthesis and tyrosinase activity in
a dose-dependent manner. The lotus flower essential
oil induced the expression of tyrosinase, microphthalmia-
associated transcription factor M (MITF-M), and
tyrosinase-related proten-2 (TRP-2) proteins, but not
tyrosinase mRNA. Moreover, it increased the phosphorylation
of ERK and cAMP response element binding
protein (CREB). In order to verify the effective components
of the lotus flower oil, its lipid composition
was assessed. It was found to be comprised of palmitic
acid methyl ester (22.66%), linoleic acid methyl ester
(11.16%), palmitoleic acid methyl ester (7.55%) and linolenic
acid methyl ester (5.16%). Among these components,
palmitic acid methyl ester clearly induced
melanogenesis as the result of increased tyrosinase
expression, thereby indicating that it may play a role
in the regulation of melanin content. Thus, our results
indicate that lotus flower oil may prove useful in the development
of gray hair prevention agents or tanning
reagents.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Ando H / 1995 / Correlation between the number of melanosomes, tyrosinase mRNA levels, and tyrosinase activity in cultured murine melanoma cells in response to various melano
Ando H / 2004 / Fatty acids regulate pigmentation via proteasomal degradation of tyrosinase: a new aspect of ubiquitin-proteasome function / J Biol Chem 279 : 15427 ~ 15433
Bertolotti A / 1998 / EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and s
Bi Y / 2006 / Characterization of the chemical composition of lotus plumule oil / J Agric Food Chem 54 : 7672 ~ 7677
Borgi W / 2007 / Antiulcerogenic activity of Zizyphus lotus (L.) extracts / J Ethnopharmacol 112 : 228 ~ 231
Ando H / 2004 / Fatty acids regulate pigmentation via proteasomal degradation of tyrosinase: a new aspect of ubiquitin-proteasome function / J Biol Chem 279 : 15427 ~ 15433
Bertolotti A / 1998 / EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and s
Bi Y / 2006 / Characterization of the chemical composition of lotus plumule oil / J Agric Food Chem 54 : 7672 ~ 7677
Borgi W / 2007 / Antiulcerogenic activity of Zizyphus lotus (L.) extracts / J Ethnopharmacol 112 : 228 ~ 231
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