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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 240 - 245 (6page)
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Aloe vera extract was fermented by Lactobacillus casei. The ability of fermented Aloe vera (FAV) as an antioxidant to protect against CCl4-induced oxidative stress and hepatotoxicity in rats was investigated. The rats were administered orally with various doses of FAV with 50, 100 mg/kg for 14 consecutive days. For this study, we not only tested activity of various plasma enzymes (AST, ALT), which are used as indicators of liver disease, but also checked thse change of liver components such as superoxide dismutase and catalase activity. Pretreatment of FAV for two weeks significantly reduced the elevated plasma enzyme activities induced by CCl4. Pretreatment of FAV also restored the hepatic enzyme, malonedialdehyde (MDA) formation. The results indicate that FAV has a protective effect against acute hepatotoxicity induced by the administration of CCl4 in rats, and that the hepatoprotective effects of FAV may be due to both the inhibition of lipid peroxidation and the increase of antioxidant activity
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참고문헌 (26)
참고문헌 신청
Abei, H. E. / 1983 / CAT. Insight. In Method of Enzymatic Analysis, Third edition. Vol. 3. Verlag. Chemi. Weinheim, 273
Balazs, T. / 1961 / Hepatic tests in toxicity studies on rats / Toxicol. Appl. Pharmacol 3 : 71 ~ 79
Boulos, L. / 1983 / Medicinal plants of north africa / Algonac Ml Reference Publications : 3 ~ 92
Bradford, M. M. / 1976 / A rapid and sensitive mehod for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding / J. Anal. Biochem
Brown, J. S. / 1991 / The use of botanicals for health purpose by members of a prepaid health plan / Research Nur. & Health 14 : 339 ~ 347
Balazs, T. / 1961 / Hepatic tests in toxicity studies on rats / Toxicol. Appl. Pharmacol 3 : 71 ~ 79
Boulos, L. / 1983 / Medicinal plants of north africa / Algonac Ml Reference Publications : 3 ~ 92
Bradford, M. M. / 1976 / A rapid and sensitive mehod for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding / J. Anal. Biochem
Brown, J. S. / 1991 / The use of botanicals for health purpose by members of a prepaid health plan / Research Nur. & Health 14 : 339 ~ 347
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