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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 282 - 291 (10page)
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초록· 키워드
오류제보하기
Pure-phase beta-tricalcium phosphate(β-TCP) proved to be a bone regeneration material, providing the patient with vital bone at the defect site in a reasonable time, making a second surgical procedure for bone harvesting unnecessary. This study compares bone healing and BMP 2/4 expression in cranial defects in rabbits grafted with autogenous bone and β-TCP.
Thirty New Zealand White rabbits was divided into 3 group of 10 animals each. Bilateral calvarial defects were made in the parietal bones of each animal. β-TCP placed in one defect and the other defects was filled with autogenous bone. The animal were sacrificed at 4, 8 and 12 weeks. Immunohistochemical analysis was used to investigate the expression of BMP 2/4.
1. The new bone formation around autogenous bone from 4 weeks and β-TCP from 8 weeks.
2. In autogenous bone graft, BMP 2/4 expression was decreased from 4 to 12 weeks
3. In β-TCP graft, BMP 4 expression was increased from 8 to 12 weeks. But, BMP 2 was observed from 12 weeks.
This study showed that bone healing, regeneration and, BMP 2/4 expression are delayed in grafted β-TCP than autogenous bone.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
/ / Biology of bone induction and its clinical applications : 739 ~ 753
/ 1986;205 / Quantitative camparision of healing in cranial fresh autografts and allografts in canine skull defects : 269 ~ 291
/ 1987;225 / Nature history of autograft and allograft : 7 ~ 16
/ 1995 / The effect of two delivery systems for recombinant human bone morphogenic protein-2 on periodontal regeneration in vivo 66 : 131 ~ 138
/ 1995 / The effects of bone morphogenic protein-2 4 and 6 on differentiation of rat osteoblastic cell in vitro 136 : 2671 ~ 2677
/ 1986;205 / Quantitative camparision of healing in cranial fresh autografts and allografts in canine skull defects : 269 ~ 291
/ 1987;225 / Nature history of autograft and allograft : 7 ~ 16
/ 1995 / The effect of two delivery systems for recombinant human bone morphogenic protein-2 on periodontal regeneration in vivo 66 : 131 ~ 138
/ 1995 / The effects of bone morphogenic protein-2 4 and 6 on differentiation of rat osteoblastic cell in vitro 136 : 2671 ~ 2677
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