지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 10 - 16 (7page)
이용수
초록· 키워드
오류제보하기
Objective The aim of this study was to compare midtrimester maternal plasma concentrations of angiopoietin 1, angiopoietin 2, andplacental growth factor between pregnant women who subsequently developed preeclampsia and those who did not.
MethodsMidtrimester maternal plasma was collected and stored at -70°C when genetic amniocentesis was performed. Cases included37 samples of individual who subsequently developed preeclampsia, and matched controls were from individuals who didnot develop preeclampsia. Angiopoietin 1, angiopoietin 2, and placental growth factor concentrations were measured bythe enzyme-linked immunosorbent assay method and were compared using the Mann-Whitney U-test. A P-value <0.05 wasconsidered significant.
ResultsIn pregnant women who subsequently developed preeclampsia, midtrimester maternal plasma concentrationsof angiopoietin 1 and angiopoietin 2 were significantly higher and placental growth factor concentrations weresignificantly lower than in women who did not develop preeclampsia (angiopoietin 1: 10.6 [3.1–19.7] vs. 7.8 [0.9–24.4]ng/mL, P=0.031; angiopoietin 2: 31.0 [4.7–81.2] vs. 18.4 [4.2–49.7] ng/mL, P<0.001; placental growth factor: 87.1 [14.2–774.3] vs. 148.8 [57.2–425.6] pg/mL, P<0.001). Within the case group who subsequently developed preeclampsia, theplacental growth factor was significantly lower in those who had fetal growth restrictions than in those who did not(placental growth factor: 72.5 [14.2–774.3] vs. 140.9 [44.2–257.5] pg/mL, P=0.003).
Conclusion Midtrimester maternal plasma concentrations of angiopoietin 1, angiopoietin 2, and placental growth factor may beassociated with the subsequent development of preeclampsia.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
ACOG Committee on Obstetric Practice. / 2002 / ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. American College of Ob
Bolin M. / 2009 / Angiopoietin-1/angiopoietin-2 ratio for prediction of preeclampsia / Am J Hypertens 22 : 891 ~ 895
Erez O. / 2008 / The change in concentrations of angiogenic and antiangiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the s
Geva E. / 2002 / Human placental vascular development : vasculogenic and angiogenic(branching and nonbranching)transformation is regulated by vascular endothelial growth fac
Hirokoshi K. / 2005 / Increase of serum angiopoietin- 2 during pregnancy is suppressed in women with preeclampsia / Am J Hypertens 18 (9 Pt 1) : 1181 ~ 1188
Bolin M. / 2009 / Angiopoietin-1/angiopoietin-2 ratio for prediction of preeclampsia / Am J Hypertens 22 : 891 ~ 895
Erez O. / 2008 / The change in concentrations of angiogenic and antiangiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the s
Geva E. / 2002 / Human placental vascular development : vasculogenic and angiogenic(branching and nonbranching)transformation is regulated by vascular endothelial growth fac
Hirokoshi K. / 2005 / Increase of serum angiopoietin- 2 during pregnancy is suppressed in women with preeclampsia / Am J Hypertens 18 (9 Pt 1) : 1181 ~ 1188
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Prevalence and associated factors of preeclampsia among pregnant women attending anti-natal care at Mettu Karl referal hospital, Ethiopia: cross-sectional study
Clinical Hypertension
2019 .01
-
A study to compare maternal and perinatal outcome in early vs. late onset preeclampsia
Obstetrics & Gynecology Science
2020 .01
-
Differences in clinical presentation and pregnancy outcomes in antepartum preeclampsia and new-onset postpartum preeclampsia: Are these the same disorder?
Obstetrics & Gynecology Science
2016 .01
-
Significance of Tissue Expression and Serum Levels of Angiopoietin-like Protein 4 in Breast Cancer Progression: Link to NF-κB /P65 Activity and Pro-Inflammatory Cytokines
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Red cell distribution width and preeclampsia: a systematic review and meta-analysis
Clinical Hypertension
2019 .01
-
Nonlinear analysis of heart rhythm in preeclampsia: a route for translational clinical applications in neuroinflammation
Clinical Hypertension
2022 .01
-
Is preeclampsia itself a risk factor for the development of metabolic syndrome after delivery?
Obstetrics & Gynecology Science
2019 .01
-
메틸수은 노출이 흰쥐의 태반 효율과 태아 성장에 미치는 영향
한국환경보건학회지
2020 .08
-
The association between preeclampsia and autism spectrum disorders among children: a meta-analysis
Clinical and Experimental Pediatrics
2019 .01
-
The association between risk of severe preeclampsia and maternal exposure to air pollutants in Seoul metropolitan city, Republic of Korea : National Health Insurance Service–National Sample Cohort (NHI-NSC) study
환경독성보건학회 심포지엄 및 학술대회
2016 .10
-
Obstructive Sleep Apnea Is Associated With Late-Onset Preeclampsia in Overweight Pregnant Women in Korea
Journal of Korean Medical Science
2023 .01
-
전자간증과 기관지폐 형성 이상
Perinatology
2015 .01
-
Oxytocin-associated signaling is related in the clinical symptoms of pregnancy with preeclampsia
한국실험동물학회 학술발표대회 논문집
2020 .02
-
Oxytocin-related signaling is involved in the clinical symptoms of pregnancy with preeclampsia
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Evidence of Placental Villous Inflammation and Apoptosis in Third-Trimester Symptomatic SARS-CoV-2 Maternal Infection
Yonsei Medical Journal
2024 .04
-
Acute Atherosis of the Uterine Spiral Arteries: Clinicopathologic Implications
Journal of Pathology and Translational Medicine
2015 .01
-
Placental expression of D6 decoy receptor in preeclampsia
Obstetrics & Gynecology Science
2015 .01
-
Placental growth factor mediates rheumatoid arthritis by regulating TH17 production and angiogenesis
한국실험동물학회 학술발표대회 논문집
2020 .07
-
Erratum : Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin- Induced Acute Lung Injury in Rats
Yonsei Medical Journal
2022 .06
-
만성고혈압 임신부의 혈장 안지오포이에틴-1과안지오포이에틴-2의 변화
Perinatology
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0