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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 325 - 330 (6page)
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초록· 키워드
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Purpose: To report the frequency and clinical features of sterile inflammation after intravitreal aflibercept injection in a Korean population.
Methods: A single-center, retrospective study was performed in patients who received intravitreal aflibercept from July 2013 through January 2015.
Results: A total of four cases of post-injection sterile inflammation were identified from 723 aflibercept injections in 233 patients. Patients presented 1 to 13 days after intravitreal aflibercept injection (mean, 5 days). The mean baseline visual acuity was 20 / 60, which decreased to 20 / 112 at diagnosis but ultimately recovered to 20 / 60. Three cases had inflammatory cells in the anterior chamber (mean, 2.25+; range, 0 to 4+), and all cases had vitritis (mean, 3+; range, 2+ to 4+). No patients had pain. Only one patient underwent anterior chamber sampling (culture negative) and injection of antibiotics. Three of four patients were treated with a topical steroid, and all experienced improvement in their symptoms and signs of inflammation.
Conclusions: The overall incidence of sterile inflammation after intravitreal aflibercept injection in a Korean population was 4 of 723 injections (0.55%), or 4 of 233 patients (1.79%). Sterile inflammation after intravitreal aflibercept injection typically presents without pain, and the visual outcomes are generally favorable.
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참고문헌 (23)
참고문헌 신청
Antoszyk AN / 2008 / Ranibizumab combined with verteporfin photodynamic therapy in
Bakri SJ / 2008 / Intraocular inflammation following intravitreal injection of bevacizumab / Graefes Arch Clin Exp Ophthalmol 246 : 779 ~ 781
Brown DM / 2006 / Ranibizumab versus verteporfin for neovascular age-related macular degeneration / N Engl J Med 355 : 1432 ~ 1444
Brown DM / 2010 / Ranibizumab for macular edema following central retinal vein occlusion:six-month primary end point results of a phase III study / Ophthalmology 117 : 1124 ~
Brown DM / 2013 / Long-term outcomes of ranibizumab therapy for diabetic macular edema: the 36-month results from two phase III trials:RISE and RIDE / Ophthalmology 120 : 201
Bakri SJ / 2008 / Intraocular inflammation following intravitreal injection of bevacizumab / Graefes Arch Clin Exp Ophthalmol 246 : 779 ~ 781
Brown DM / 2006 / Ranibizumab versus verteporfin for neovascular age-related macular degeneration / N Engl J Med 355 : 1432 ~ 1444
Brown DM / 2010 / Ranibizumab for macular edema following central retinal vein occlusion:six-month primary end point results of a phase III study / Ophthalmology 117 : 1124 ~
Brown DM / 2013 / Long-term outcomes of ranibizumab therapy for diabetic macular edema: the 36-month results from two phase III trials:RISE and RIDE / Ophthalmology 120 : 201
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