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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 543 - 547 (5page)
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Background: The recurrence rate of rosacea was not known very well, but has been reported as 60% in 6 months after withdrawal of the drug. It is not known which treatment can reduce relapses of rosacea effectively. Objective: The objective was to identify whether 595 nm-pulsed dye laser (PDL) treatment reduced recurrence rate among rosacea patients who were treated with oral minocycline. Methods: One hundred and seven Korean patients with rosacea who started treatment with oral minocycline (100 mg/d) with or without PDL (2∼4 sessions) were evaluated retrospectively.
The recurrence rate was estimated using the Kaplan-Meier method, and difference was evaluated using the log-rank test. Cox proportional hazards model was used to estimate hazard ratios and 95% confidence intervals (CIs) of risk factors for the recurrence of rosacea. Results: The recurrencefree survival analysis revealed that the group with oral minocycline plus PDL was significantly different compared with the group with oral minocycline alone (p=0.011). Cox proportional hazards model showed that the combined use of PDL with oral minocycline appeared to be a significant protective factor for the hazard of recurrence of rosacea (hazard ratio, 0.492; 95% CI, 0.257∼0.941; p=0.032). Conclusion: PDL can be used added to oral minocycline to reduce relapses among rosacea patients who are undergoing oral minocycline treatment.
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참고문헌 (18)
참고문헌 신청
Aksoy B / 2010 / The impact of rosacea on quality of life: effects of demographic and clinical characteristics and various treatment modalities / Br J Dermatol 163 : 719 ~ 7
Bernstein EF / 2008 / Rosacea treatment using the new-generation, high-energy, 595 nm, long pulse-duration pulsed-dye laser / Lasers Surg Med 40 : 233 ~ 239
Del Rosso JQ / 2007 / Two randomized phase III clinical trials evaluating anti-inflammatory dose doxycycline (40-mg doxycycline, USP capsules) administered once daily for tre
Erceg A / 2013 / The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review / J Am Acad Dermatol 69 : 609.e8 ~ 615.e8
Jackson JM / 2013 / Efficacy of extendedrelease 45 mg oral minocycline and extended-release 45mg oral minocycline plus 15% azelaic acid in the treatment of acne rosacea / J D
Bernstein EF / 2008 / Rosacea treatment using the new-generation, high-energy, 595 nm, long pulse-duration pulsed-dye laser / Lasers Surg Med 40 : 233 ~ 239
Del Rosso JQ / 2007 / Two randomized phase III clinical trials evaluating anti-inflammatory dose doxycycline (40-mg doxycycline, USP capsules) administered once daily for tre
Erceg A / 2013 / The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review / J Am Acad Dermatol 69 : 609.e8 ~ 615.e8
Jackson JM / 2013 / Efficacy of extendedrelease 45 mg oral minocycline and extended-release 45mg oral minocycline plus 15% azelaic acid in the treatment of acne rosacea / J D
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