지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 167 - 171 (5page)
이용수
초록· 키워드
오류제보하기
Background: The etiology of porokeratosis (PK) remains unknown, but immunosuppression
is known to be a factor in the pathogenesis of PK and it may also exacerbate PK.
Objective: The aim of this study was to examine the clinical characteristics of PK associated
with immunosuppressive therapy in renal transplant recipients.
Methods: A total of 9 renal transplant patients diagnosed with biopsy-proven PK from January
2001 to December 2006 were enrolled. The authors analyzed the patient and medication histories,
clinical characteristics, and associated diseases.
Results: The ages of the 9 patients ranged from 38 to 67 years (mean 52 years). All received
multi-drug regimens comprised of two or three immunosuppressive agents (steroids, cyclosporine,
mycophenolate mofetil, azathioprine and/or tacrolimus). Times between transplantation and the
onset of PK ranged from 2 to 9 years (mean 4.1 years). No family history of PK or a history
of intense sun-exposure was elicited. The number of the lesions was less than ten in 8 of the
9. Lesions were mainly located in the extremities, though some affected the trunk or neck (3).
Three patients had disseminated superficial actinic PK (DSAP), PK Mibelli, or both types.
Associated diseases included verruca (4), recurrent herpes simplex (1), actinic keratosis (1), and
cutaneous B cell lymphoma (1).
Conclusion: The three clinical patterns of PK occurred equally in our patients, namely,
coexistent PK Mibelli and DSAP, or the DSAP and Mibelli types as independent forms. Our
findings support the notion that the different variants of PK be viewed as parts of a heterogeneous
clinical spectrum. Further studies are needed in order to establish the clinical patterns of PK
in immunosuppressed patients.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Agrawal SK / 2003 / Topical tretinoin in Indian male with zosteriform porokeratosis / Int J Dermatol 42 : 919 ~ 920
Anzai S / 1999 / Squamous cell carcinoma in a renal transplant recipient with linear porokeratosis / J Dermatol 26 : 244 ~ 247
Cho YH / 1992 / A case of disseminated superficial porokeratosis in immunosuppressed kidney transplant recipient / Korean J Dermatol 30 : 539 ~ 542
Cohen EB / 1987 / Cutaneous complications in renal transplant recipients / Am J Clin Pathol 88 : 32 ~ 37
Ferrandiz C / 1995 / Epidermal dysplasia and neoplasia in kidney transplant recipients / J Am Acad Dermatol 33 : 590 ~ 596
Anzai S / 1999 / Squamous cell carcinoma in a renal transplant recipient with linear porokeratosis / J Dermatol 26 : 244 ~ 247
Cho YH / 1992 / A case of disseminated superficial porokeratosis in immunosuppressed kidney transplant recipient / Korean J Dermatol 30 : 539 ~ 542
Cohen EB / 1987 / Cutaneous complications in renal transplant recipients / Am J Clin Pathol 88 : 32 ~ 37
Ferrandiz C / 1995 / Epidermal dysplasia and neoplasia in kidney transplant recipients / J Am Acad Dermatol 33 : 590 ~ 596
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