지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 569 - 574 (6page)
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초록· 키워드
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Background: Various systemic agents have been assessed for the treatment of alopecia areata (AA); however, there is a paucity of comparative studies. Objective: To assess and compare cyclosporine and betamethasone minipulse therapy as treatments for AA with regard to effectiveness and safety. Methods: Data were collected from 88 patients who received at least 3 months of oral cyclosporine (n=51) or betamethasone minipulse therapy (n=37) for AA. Patients with ≥50% of terminal hair regrowth in the alopecic area were considered responders. Results: The responder of the cyclosporine group was 54.9% and that of the betamethasone minipulse group was 37.8%. In the cyclosporine group, patients with mild AA were found to respond better to the treatment. Based on the patient self-assessments, 70.6% of patients in the cyclosporine group and 43.2% of patients in the betamethasone minipulse group rated their hair regrowth as excellent or good. Side effects were less frequent in the cyclosporine group. Conclusion: Oral cyclosporine appeared to be superior to betamethasone minipulse therapy in terms of treatment effectiveness and safety.
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참고문헌 (23)
참고문헌 신청
Amor KT. / 2010 / The use of cyclosporine in dermatology: part I / J Am Acad Dermatol 63:925~946
Alkhalifah A. / 2010 / Alopecia areata update: part II. Treatment / J Am Acad Dermatol 62:191~202
Chao-Chun Yang / 2013 / Early Intervention with High-Dose Steroid Pulse Therapy Prolongs Disease-Free Interval of Severe Alopecia Areata:A Retrospective Study / Annals of Dermatology 25(4):471~474
Kar BR. / 2005 / Placebo-controlled oral pulse prednisolone therapy in alopecia areata / J Am Acad Dermatol 52:287~290
Kurosawa M. / 2006 / A comparison of the efficacy, relapse rate and side effects among three modalities of systemic corticosteroid therapy for alopecia areata / Dermatology 212:361~365
Alkhalifah A. / 2010 / Alopecia areata update: part II. Treatment / J Am Acad Dermatol 62:191~202
Chao-Chun Yang / 2013 / Early Intervention with High-Dose Steroid Pulse Therapy Prolongs Disease-Free Interval of Severe Alopecia Areata:A Retrospective Study / Annals of Dermatology 25(4):471~474
Kar BR. / 2005 / Placebo-controlled oral pulse prednisolone therapy in alopecia areata / J Am Acad Dermatol 52:287~290
Kurosawa M. / 2006 / A comparison of the efficacy, relapse rate and side effects among three modalities of systemic corticosteroid therapy for alopecia areata / Dermatology 212:361~365
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