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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.10
- 수록면
- 303 - 310 (8page)
이용수
초록· 키워드
오류제보하기
We are exposed to numerous xenobiotic electrophiles on a daily basis through the environment, lifestyle, and dietary habits. Although such reactive species have been associated with detrimental effects, recent accumulated evidence indicates that xenobiotic electrophiles appear to act as signaling molecules. In this review, we introduce our findings on 1) activation of various redox signaling pathways involved in cell proliferation, detoxification/excretion of electrophiles, quality control of cellular proteins, and cell survival during exposure to xenobiotic electrophiles at low concentrations through covalent modification of thiol groups in sensor proteins, and 2) negative regulation of reactive sulfur species (RSS) in the modulation of redox signaling and toxicity caused by xenobiotic electrophiles.
목차
Abstract
INTRODUCTION
ARE ELECTROPHILES GOOD OR BAD?
MODULATION OF REDOX SIGNALING PATHWAYS THROUGH COVALENT MODIFICATION OF SENSOR PROTEINS
REACTIVE SULFUR SPECIES AS POTENTIAL REGULATORS THAT REPRESS REACTIVITY OF XENOBIOTIC ELECTROPHILES
CONCLUSIONS
REFERENCES
참고문헌 (72)
참고문헌 신청
Eiguren-Fernandez, A. / 2008 / Atmospheric distribution of gas- and particlephase quinones in Southern California / Aerosol Sci. Tech 42:854~861
Chung, M. Y. / 2006 / Aerosol-borne quinones and reactive oxygen species generation by particulate matter extracts / Environ. Sci. Technol 40:4880~4886
Jakober, C. A. / 2007 / Quinone emissions from gasoline and diesel motor vehicles / Environ. Sci. Technol 41:4548~4554
Shinyashiki, M. / 2009 / Electrophilic and redox properties of diesel exhaust particles / Environ. Res 109:239~244
Talhout, R. / 2011 / Hazardous compounds in tobacco smoke / Int. J. Environ. Res. Public Health 8:613~628
Chung, M. Y. / 2006 / Aerosol-borne quinones and reactive oxygen species generation by particulate matter extracts / Environ. Sci. Technol 40:4880~4886
Jakober, C. A. / 2007 / Quinone emissions from gasoline and diesel motor vehicles / Environ. Sci. Technol 41:4548~4554
Shinyashiki, M. / 2009 / Electrophilic and redox properties of diesel exhaust particles / Environ. Res 109:239~244
Talhout, R. / 2011 / Hazardous compounds in tobacco smoke / Int. J. Environ. Res. Public Health 8:613~628
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