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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 246 - 248 (3page)
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초록· 키워드
오류제보하기
Chryseobacterium hominis is non-fermenting Gram-negative rod that was first identified as a novel species in 2007. Here, we report the first clinical case of C. hominis bacteremia, which was confirmed by MALDI-TOF MS and 16S rRNA gene sequencing. A 16-year-old boy diagnosed with acute lymphoblastic leukemia was hospitalized for three months. Two sets of blood culture test through a peripherally inserted central catheter (PICC), which was inserted a month ago, was performed when his white blood cell count declined and he had a high fever. Colonies of medium sizes that looked round, mucoid, sticky, and grayish on blood and chocolate agar plates were observed. Identification of bacteria using the VITEK MALDI-TOF MS system (BioMérieux, France) was not successful and the VITEK 2 system (BioMérieux, USA) indicated Sphingomonas paucimobilis, with a questionable level of confidence (92%). However, Microflex LT Biotyper (Bruker Daltonics, Germany) showed C. homins (log score: 1.81) and sequence of 16S rRNA showed a 100% identity with C. hominis. Piperacillin-tazobactam was administered since the isolate was susceptible to piperacillin-tazobactam but C. hominis showed growth in the next four follow-up culture of blood drawn through PICC. The fever subsided only after PICC was changed. The clinical prognosis and antimicrobial susceptibility test of C. hominis should be further studied.
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참고문헌 (5)
참고문헌 신청
Vaneechoutte M / 2007 / Chryseobacterium hominis sp. nov., to accommodate clinical isolates biochemically similar to CDC groups II-h and II-c / Int J Syst Evol Microbiol 57:2623~2628
Clinical and Laboratory Standards Institute / 2017 / Performance standards for antimicrobial susceptibility testing. 27th ed. CLSI supplement M100 / Clinical and Laboratory Standards Institute
Bloch KC / 1997 / Chryseobacterium meningosepticum: an emerging pathogen among immunocompromised adults. Report of 6 cases and literature review / Medicine (Baltimore) 76:30~41
Chiu CH / 2000 / Atypical Chryseobacterium meningosepticum and meningitis and sepsis in newborns and the immunocompromised, Taiwan / Emerg Infect Dis 6:481~486
Kirby JT / 2004 / Antimicrobial susceptibility and epidemiology of a worldwide collection of Chryseobacterium spp.: report from the SENTRY Antimicrobial Surveillance Program (1997-2001) / J Clin Microbiol 42:445~448
Clinical and Laboratory Standards Institute / 2017 / Performance standards for antimicrobial susceptibility testing. 27th ed. CLSI supplement M100 / Clinical and Laboratory Standards Institute
Bloch KC / 1997 / Chryseobacterium meningosepticum: an emerging pathogen among immunocompromised adults. Report of 6 cases and literature review / Medicine (Baltimore) 76:30~41
Chiu CH / 2000 / Atypical Chryseobacterium meningosepticum and meningitis and sepsis in newborns and the immunocompromised, Taiwan / Emerg Infect Dis 6:481~486
Kirby JT / 2004 / Antimicrobial susceptibility and epidemiology of a worldwide collection of Chryseobacterium spp.: report from the SENTRY Antimicrobial Surveillance Program (1997-2001) / J Clin Microbiol 42:445~448
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