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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제22권 제3호
- 발행연도
- 2019.1
- 수록면
- 282 - 290 (9page)
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초록· 키워드
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Characterizing inflammation and fibrosis in Crohn's disease (CD) is necessary to guide clinical management, but distinguishing the two remains challenging. Novel ultrasound (US) techniques: contrast-enhanced US (CEUS) and shear wave elastography (SWE) offer great potential in evaluating disease activity in pediatric patients. Three patients ages 16 to 20 with known CD underwent CEUS and SWE to characterize bowel wall inflammation and fibrosis. Magnetic resonance enterography, endoscopy, or surgical pathology findings are also described when available. The patients' disease activity included acute inflammation, chronic inflammation with stricture formation, and a fibrotic surgical anastomosis without inflammation. CEUS was useful in determining the degree of inflammation, and SWE identified bowel wall fibrosis. Used together these techniques allow for better characterization of the degree of fibrosis and inflammation in bowel strictures. With further validation CEUS and SWE may allow for improved characterization of bowel strictures and disease flares in pediatric patients suffering from CD.
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등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Kappelman MD / 2007 / The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States / Clin Gastroenterol Hepatol 5:1424~1429
Rieder F / 2013 / Crohn's disease complicated by strictures : a systematic review / Gut 62:1072~1084
Malgras B / 2015 / Multidisciplinary management of gastrointestinal fibrotic stenosis in Crohn's disease / Dig Dis Sci 60:1152~1168
Conti CB / 2017 / Role of bowel ultrasound in the diagnosis and follow-up of patients with Crohn's disease / Ultrasound Med Biol 43:725~734
Yusuf GT / 2017 / Retrospective analysis of the safety and cost implications of pediatric contrast-enhanced ultrasound at a single center / AJR Am J Roentgenol 208:446~452
Rieder F / 2013 / Crohn's disease complicated by strictures : a systematic review / Gut 62:1072~1084
Malgras B / 2015 / Multidisciplinary management of gastrointestinal fibrotic stenosis in Crohn's disease / Dig Dis Sci 60:1152~1168
Conti CB / 2017 / Role of bowel ultrasound in the diagnosis and follow-up of patients with Crohn's disease / Ultrasound Med Biol 43:725~734
Yusuf GT / 2017 / Retrospective analysis of the safety and cost implications of pediatric contrast-enhanced ultrasound at a single center / AJR Am J Roentgenol 208:446~452
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