지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 518 - 523 (6page)
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초록· 키워드
오류제보하기
Background/Aims: Patients with small bowel strictures have varied etiologies, including malignancy. Little data are available on the demographic profiles and etiologies of small bowel strictures in patients who undergo surgery because of intestinal obstruction but do not have a definitive pre-operative diagnosis. Methods: Retrospective data were analyzed for all patients operated between January 2000 and October 2014 for small bowel strictures without mass lesions and a definite diagnosis after imaging and endoscopic examinations. Demographic parameters, imaging, endoscopic, and histological data were extracted from the medical records. Univariate and multivariate analyses were conducted to identify factors that could differentiate between intestinal tuberculosis (ITB) and Crohn’s disease (CD) and between malignant and benign strictures. Results: Of the 7,425 reviewed medical records, 89 met the inclusion criteria. The most common site of strictures was the proximal small intestine (41.5%). The most common histological diagnoses in patients with small bowel strictures were ITB (26.9%), CD (23.5%), non-specific strictures (20.2%), malignancy (15.5%), ischemia (10.1%), and other complications (3.4%). Patients with malignant strictures were older than patients with benign etiologies (47.6±15.9 years vs. 37.4±16.4 years, P=0.03) and age >50 years had a specificity for malignant etiology of 80%. Only 7.1% of the patients with malignant strictures had more than 1 stricture and 64% had proximally located strictures. Diarrhea was the only factor that predicted the diagnosis of CD 6.5 (95% confidence interval, 1.10-38.25; P=0.038) compared with the diagnosis of ITB. Conclusions: Malignancy was the cause of small bowel strictures in approximately 16% patients, especially among older patients with a single stricture in the proximal location. Empirical therapy should be avoided and the threshold for surgical resection is low in these patients.
목차
등록된 정보가 없습니다.
참고문헌 (8)
참고문헌 신청
Kelly ME / 2005 / Small-bowel diaphragm disease: seven surgical cases / Arch Surg 140:1162~1166
Wang ML / 2011 / Special diaphragm-like strictures of small bowel unrelated to nonsteroidal anti-inflammatory drugs / World J Gastroenterol 17:3596~3604
Patel S / 2009 / Small intestinal strictures as a complication of mesenteric vessel thrombosis: two case reports / J Med Case Rep 3:8623
Honzawa Y / 2010 / Successful endoscopic dilation treatment of small intestinal stricture occurring during chemotherapy for malignant lymphoma / Case Rep Gastroenterol 4:323~329
Ahuja V / 2010 / Inflammatory bowel disease in the Asia-Pacific area: a comparison with developed countries and regional differences / J Dig Dis 11:134~147
Wang ML / 2011 / Special diaphragm-like strictures of small bowel unrelated to nonsteroidal anti-inflammatory drugs / World J Gastroenterol 17:3596~3604
Patel S / 2009 / Small intestinal strictures as a complication of mesenteric vessel thrombosis: two case reports / J Med Case Rep 3:8623
Honzawa Y / 2010 / Successful endoscopic dilation treatment of small intestinal stricture occurring during chemotherapy for malignant lymphoma / Case Rep Gastroenterol 4:323~329
Ahuja V / 2010 / Inflammatory bowel disease in the Asia-Pacific area: a comparison with developed countries and regional differences / J Dig Dis 11:134~147
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