지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 359 - 365 (7page)
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초록· 키워드
오류제보하기
Purpose: To investigate the foveal avascular zone (AVZ), superficial and deep foveal and parafoveal vesseldensity (VD) changes related to diabetic retinopathy. Methods: Forty-nine type 2 diabetes mellitus (DM) and 45 healthy control subjects were included in this study. The demographic data (age and sex), disease duration, and level of glycated hemoglobin were collected. SuperficialVD (%), superficial AVZ area (mm2), deep VD (%) and deep AVZ area (mm2) were evaluated via opticcoherence tomography angiography. Results: Superficial AVZ was 0.438 ± 0.05 mm2 in the DM group, 0.246 ± 0.022 mm2 in the control group (p< 0.001). Deep AVZ was 0.732 ± 0.06 mm2 in the DM group, and 0.342 ± 0.022 mm2 in the control group (p< 0.001). Superficial foveal VD was 29.45 ± 0.76 mm2 in the DM group, and 34.86 ± 0.75 mm2 in the controlgroup (p < 0.001). Deep foveal VD was 24.85 ± 1.08 mm2 in the DM group, and 33.47 ± 0.56 mm2 in the controlgroup (p < 0.001). Conclusions: In this study, we demonstrated an enlargement in the foveal AVZ along with a reduction in thevascular density of the superficial and deep capillary network in the foveal and parafoveal area using optic coherencetomography angiography in patients with nonproliferative diabetic retinopathy. This technique can beused to monitor the progression of the disease and to evaluate the response to treatment.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Wylegala A / 2016 / Optical coherence angiography: a review / Medicine (Baltimore) 95:e4907
Kim DY / 2013 / Optical imaging of the chorioretinal vasculature in the living human eye / Proc Natl Acad Sci U S A 110:14354~14359
Coscas G / 2016 / Heidelberg Spectralis optical coherence tomography angiography : technical aspects / Dev Ophthalmol 56:1~5
Jia Y / 2015 / Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye / Proc Natl Acad Sci U S A 112:E2395~E2402
Spaide RF / 2015 / Retinal vascular layers imaged by fluorescein angiography and optical coherence tomography angiography / JAMA Ophthalmol 133:45~50
Kim DY / 2013 / Optical imaging of the chorioretinal vasculature in the living human eye / Proc Natl Acad Sci U S A 110:14354~14359
Coscas G / 2016 / Heidelberg Spectralis optical coherence tomography angiography : technical aspects / Dev Ophthalmol 56:1~5
Jia Y / 2015 / Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye / Proc Natl Acad Sci U S A 112:E2395~E2402
Spaide RF / 2015 / Retinal vascular layers imaged by fluorescein angiography and optical coherence tomography angiography / JAMA Ophthalmol 133:45~50
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