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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
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- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제29권 제7호
- 발행연도
- 2019.1
- 수록면
- 1,014 - 1,021 (8page)
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In the bacterial community, unicellular organisms act together as a multicellular being. Bacteria interact within the community and programmed cell death (PCD) in prokaryotes is a sort of altruistic action that enables the whole population to thrive. Genetically, encoded cell death pathways are triggered by DNA damage or nutrient starvation. Given the environmental and bacterial diversity, different PCD mechanisms are operated. Still, their biochemical and physiological aspects remain unrevealed. There are three main pathways; thymineless death, apoptosis-like death, and toxin-antitoxin systems. The discovery of PCD in bacteria has revealed the possibility of developing new antibiotics. In this review, the molecular and physiological characteristics of the three types of PCD and their development potential as antibacterial agents are addressed.
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참고문헌 (46)
참고문헌 신청
Tanouchi Y / 2013 / Programmed cell death in bacteria and implications for antibiotic therapy / Trends Microbiol 21:265~270
Allocati N / 2015 / Die for the community: an overview of programmed cell death in bacteria / Cell Death Dis 6:e1609
Bayles KW / 2014 / Bacterial programmed cell death: making sense of a paradox / Nat. Rev. Microbiol 12:63~69
Dewachter L / 2016 / The bacterial cell cycle checkpoint protein Obg and its role in programmed cell death / Microb. Cell 3:255~256
Andryukov BG / 2018 / Molecular and genetic characteristics of cell death in prokaryotes / Mol. Genet. Microbiol 33:73~83
Allocati N / 2015 / Die for the community: an overview of programmed cell death in bacteria / Cell Death Dis 6:e1609
Bayles KW / 2014 / Bacterial programmed cell death: making sense of a paradox / Nat. Rev. Microbiol 12:63~69
Dewachter L / 2016 / The bacterial cell cycle checkpoint protein Obg and its role in programmed cell death / Microb. Cell 3:255~256
Andryukov BG / 2018 / Molecular and genetic characteristics of cell death in prokaryotes / Mol. Genet. Microbiol 33:73~83
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