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Measuring T1 contrast in ex-vivo prostate tissue at the Earth's magnetic field
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논문 기본 정보

Type
Academic journal
Author
Journal
Korean Magnetic Resonance Society Journal of the Korean Magnetic Resonance Society Journal of the Korean Magnetic Resonance Society 제23권 제1호 KCI Accredited Journals
Published
2019.1
Pages
12 - 19 (8page)

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Measuring T1 contrast in ex-vivo prostate tissue at the Earth's magnetic field
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A former study has shown that the spin-lattice relaxation time (T1) in cancerous prostate tissue had enhanced contrast at an ultra-low magnetic field, 132 uT. To study the field dependence and the origin of the contrast we measured T1 in pairs of ex-vivo prostate tissues at the Earth’s magnetic field. A portable and coil-based nuclear magnetic resonance (NMR) system was adopted for T1 measurements at 40 uT. The T1 contrast, delta = 1 - T1 (more cancer)/T1(less cancer), was calculated from each pair. Additionally, we performed pathological examinations such as Gleason’s score, cell proliferation index, and micro-vessel density (MVD), to quantify correlations between the pathological parameters and T1 of the cancerous prostate tissues.

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References (30)

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American Cancer Society / 2017 / Cancer Facts & Figures 2017 / American Cancer Society google schola S. Verma / 2011 / AJR Am. J. Roentgenol 196:S1 google schola H. U. Ahmed / 2017 / Lancet 389:815 google schola P. Y. Poon / 1985 / Radiology 154:143 google schola H. Hricak / 1987 / Radiology 162:331 google schola

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