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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 344 - 351 (8page)
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초록· 키워드
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ObjectiveThe purpose of this study was to evaluate the effectiveness of scheduled ramosetron injections for controllingpostoperative nausea and vomiting (PONV) after single-port access total laparoscopic hysterectomy (SPA-TLH). MethodsNinety patients who underwent SPA-TLH at the Korean National Health Insurance Service Ilsan Hospital between June2013 and July 2014 were enrolled in this prospective, randomized, double-blinded, placebo-controlled study. Thepatients were divided into 2 groups as follows: the ramosetron group (0.3 mg intravenously [IV]; n=45) and the placebogroup (normal saline IV; n=45). Both groups received their respective injections 12 and 24 hours post surgery. Theincidence and severity of PONV (numerical rating scale, 0–10), and the use of rescue antiemetics post surgery wereevaluated. ResultsDemographic and perioperative statistically significant differences were not observed between the 2 groups. Theincidence of PONV in the ramosetron and placebo groups was 46.7% and 51.1%, respectively (P=0.51). We foundsignificant differences in the severity of PONV between the 24- to 48-hour postoperative periods in both groups(ramosetron group, P=0.04 and placebo group, P=0.03). The use of rescue antiemetics was significantly lower in theramosetron group than in the placebo group (P=0.02). ConclusionAfter general anesthesia, scheduled injections of ramosetron 12 and 24 hours after SPA-TLH reduced the severity ofPONV and the use of rescue antiemetics. Administration of ramosetron can be considered not only immediately afterSPA-TLH but also during the first 24-hour recovery period. Trial RegistrationClinicalTrials.gov Identifier: NCT 02011659
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참고문헌 (24)
참고문헌 신청
Macario A / 1999 / Which clinical anesthesia outcomes are important to avoid? The perspective of patients / Anesth Analg 89:652~658
Gan TJ / 2003 / Consensus guidelines for managing postoperative nausea and vomiting / Anesth Analg 97:62~71
Rowbotham D / 1995 / Recognising risk factors / Nurs Times 91:44~46
Stadler M / 2003 / Difference in risk factors for postoperative nausea and vomiting / Anesthesiology 98:46~52
Jacobson TZ / 2004 / Safe laparoscopy : is it possible / Curr Opin Obstet Gynecol 16:283~288
Gan TJ / 2003 / Consensus guidelines for managing postoperative nausea and vomiting / Anesth Analg 97:62~71
Rowbotham D / 1995 / Recognising risk factors / Nurs Times 91:44~46
Stadler M / 2003 / Difference in risk factors for postoperative nausea and vomiting / Anesthesiology 98:46~52
Jacobson TZ / 2004 / Safe laparoscopy : is it possible / Curr Opin Obstet Gynecol 16:283~288
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