지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.98 No.1
- 발행연도
- 2020.1
- 수록면
- 7 - 14 (8page)
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초록· 키워드
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Purpose: Pancreaticoduodenectomy (PD) is recently performed in older cancer patients. The complication rate of PD is high. The present study was to compare the postoperative short- and long-term outcomes of PD in between older patients and younger patients.
Methods: Between 2000 and 2014, patients who underwent PD due to periampullary cancers were enrolled. Patients aged 75 years or over were included in the older group.
Results: Total 1,249 patients were enrolled in this study and 168 patients (13.5%) were included in the older group. Postoperative complication rates, duration of postoperative hospital stay, and 30-day mortality were comparable between the 2 groups, although the admission rate of intensive care unit postoperatively was higher in the older adult group (20.8% vs. 10.5%, P ＜ 0.001). In terms of long-term outcomes, 5-year overall survival rate was lower in the older group (23.4% vs. 41.8%, P ＜ 0.001), and 5-year cumulative recurrence rate was higher in the older group without statistical significance (63.9% vs. 57.9%, P = 0.095). However, there were no statistical differences of cumulative recurrence in pancreatic cancer patients (81.5% vs. 82.5%, P = 0.805).
Conclusion: PD for periampullary cancer is a safe and feasible treatment in the older patients. The treatment modality for obtaining better survival outcomes will be investigated.
Methods: Between 2000 and 2014, patients who underwent PD due to periampullary cancers were enrolled. Patients aged 75 years or over were included in the older group.
Results: Total 1,249 patients were enrolled in this study and 168 patients (13.5%) were included in the older group. Postoperative complication rates, duration of postoperative hospital stay, and 30-day mortality were comparable between the 2 groups, although the admission rate of intensive care unit postoperatively was higher in the older adult group (20.8% vs. 10.5%, P ＜ 0.001). In terms of long-term outcomes, 5-year overall survival rate was lower in the older group (23.4% vs. 41.8%, P ＜ 0.001), and 5-year cumulative recurrence rate was higher in the older group without statistical significance (63.9% vs. 57.9%, P = 0.095). However, there were no statistical differences of cumulative recurrence in pancreatic cancer patients (81.5% vs. 82.5%, P = 0.805).
Conclusion: PD for periampullary cancer is a safe and feasible treatment in the older patients. The treatment modality for obtaining better survival outcomes will be investigated.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (23)
참고문헌 신청
Eshuis WJ / 2014 / Antecolic versus retrocolic route of the gastroenteric anastomosis after pancreatoduodenectomy : a randomized controlled trial / Ann Surg 259:45~51
Casadei R / 2006 / Prognostic factors in periampullary and pancreatic tumor resection in elderly patients / World J Surg 30:1992~2001
강창무 / 2007 / Pancreaticoduodenectomy of Pancreatic Ductal Adenocarcinoma in the Elderly / Yonsei Medical Journal 48(3):488~494
Katai H / 1998 / The outcome of surgical treatment for gastric carcinoma in the elderly / Jpn J Clin Oncol 28:112~115
Kim DY / 2005 / Clinicopathologic characteristics of gastric carcinoma in elderly patients : a comparison with young patients / World J Gastroenterol 11:22~26
Casadei R / 2006 / Prognostic factors in periampullary and pancreatic tumor resection in elderly patients / World J Surg 30:1992~2001
강창무 / 2007 / Pancreaticoduodenectomy of Pancreatic Ductal Adenocarcinoma in the Elderly / Yonsei Medical Journal 48(3):488~494
Katai H / 1998 / The outcome of surgical treatment for gastric carcinoma in the elderly / Jpn J Clin Oncol 28:112~115
Kim DY / 2005 / Clinicopathologic characteristics of gastric carcinoma in elderly patients : a comparison with young patients / World J Gastroenterol 11:22~26
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UCI(KEPA) : I410-ECN-0101-2020-514-000260449