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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.2
- 수록면
- 25 - 31 (7page)
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초록· 키워드
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BACKGROUND/OBJECTIVES: To date, sodium intake has been evaluated based on spot urine instead of 24-hour (hr) urine collection. Nevertheless, the optimal method for assessing daily sodium intake remains unclear.
SUBJECTS/METHODS: Fifteen male (age 32.7 ± 6.5 years) participants were offered 3 meals with a total of 9-10 g salt over 24 hours, and 24-hr urine was collected from the second-void urine of the first day to the first-void urine of the second day. Twenty-four-hr urinary sodium (24UNa) was estimated using Tanaka’s equation and the Korean formula, and spot urine Na, potassium (K), chloride (Cl), urea nitrogen (UN), creatinine (Cr), specific gravity (SG) and osmolality (Osm) were measured. The ratios of urinary Na to other parameters were calculated, and correlations with total measured 24UNa were identified.
RESULTS: Average 24-hr urine volume was 1,403 ± 475 mL, and measured 24UNa was 143.9 ± 42.1 mEq (range, 87.1-239.4 mEq). Measured 24UNa was significantly correlated with urinary Na/UN (r = 0.560, P ＜ 0.01), urinary Na/Osm (r = 0.510, P ＜ 0.01), urinary Na/Cr (r = 0.392, P ＜ 0.01), urinary Na/K (r = 0.290, P ＜ 0.01), 24UNa estimated using Tanaka’s equation (r = 0.452, P ＜ 0.01) and the Korean formula (r = 0.414, P ＜ 0.01), age (r = 0.548, P ＜ 0.01), weight (r = 0.497, P ＜ 0.01), and height (r = 0.393, P ＜ 0.01) in all spot urine samples. Estimated 24UNa based on the second-void spot urine of the first day tended to be more closely correlated with measured 24UNa than were estimates from the other spot urine samples. The significant parameters correlated with the second-void urine of the first day were urinary Na/K (r = 0.647, P ＜ 0.01), urinary Na/Cr (r = 0.558, P ＜ 0.05), and estimated 24UNa using Tanaka’s equation (r = 0.616, P ＜ 0.05) and the Korean formula (r = 0.588, P ＜ 0.05).
CONCLUSIONS: Second-void urine is more reliable than first-void urine for estimating 24UNa. Urinary Na/K in the second-void urine on the first day is significantly correlated with 24UNa. Further studies are needed to establish the most reliable index and the optimal time of urine sampling for predicting 24UNa.
SUBJECTS/METHODS: Fifteen male (age 32.7 ± 6.5 years) participants were offered 3 meals with a total of 9-10 g salt over 24 hours, and 24-hr urine was collected from the second-void urine of the first day to the first-void urine of the second day. Twenty-four-hr urinary sodium (24UNa) was estimated using Tanaka’s equation and the Korean formula, and spot urine Na, potassium (K), chloride (Cl), urea nitrogen (UN), creatinine (Cr), specific gravity (SG) and osmolality (Osm) were measured. The ratios of urinary Na to other parameters were calculated, and correlations with total measured 24UNa were identified.
RESULTS: Average 24-hr urine volume was 1,403 ± 475 mL, and measured 24UNa was 143.9 ± 42.1 mEq (range, 87.1-239.4 mEq). Measured 24UNa was significantly correlated with urinary Na/UN (r = 0.560, P ＜ 0.01), urinary Na/Osm (r = 0.510, P ＜ 0.01), urinary Na/Cr (r = 0.392, P ＜ 0.01), urinary Na/K (r = 0.290, P ＜ 0.01), 24UNa estimated using Tanaka’s equation (r = 0.452, P ＜ 0.01) and the Korean formula (r = 0.414, P ＜ 0.01), age (r = 0.548, P ＜ 0.01), weight (r = 0.497, P ＜ 0.01), and height (r = 0.393, P ＜ 0.01) in all spot urine samples. Estimated 24UNa based on the second-void spot urine of the first day tended to be more closely correlated with measured 24UNa than were estimates from the other spot urine samples. The significant parameters correlated with the second-void urine of the first day were urinary Na/K (r = 0.647, P ＜ 0.01), urinary Na/Cr (r = 0.558, P ＜ 0.05), and estimated 24UNa using Tanaka’s equation (r = 0.616, P ＜ 0.05) and the Korean formula (r = 0.588, P ＜ 0.05).
CONCLUSIONS: Second-void urine is more reliable than first-void urine for estimating 24UNa. Urinary Na/K in the second-void urine on the first day is significantly correlated with 24UNa. Further studies are needed to establish the most reliable index and the optimal time of urine sampling for predicting 24UNa.
목차
INTRODUCTION
SUBJECTS AND METHODS
RESULTS
DISCUSSION
REFERENCES
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UCI(KEPA) : I410-ECN-0101-2020-594-000361578