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논문 기본 정보

자료유형
학술저널
저자정보
Mohammad Fayiz AbuMoh"d (Yarmouk University) Samir Hasan Qasim (Yarmouk University) Loay Abedalgader Salman (Jordan University)
저널정보
한국코칭능력개발원 International Journal of Coaching Science International Journal of Coaching Science Vol.14 No.1
발행연도
2020.1
수록면
54 - 63 (10page)

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초록· 키워드

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Pituitary apoplexy is a rare, life-threatening clinical syndrome caused by infarction and/or haemorrhage of the tumour. Resistance to cabergoline is rare, but it has been described in a small percentage of patients with macroprolactinoma. We report a case of apoplexy within a macroprolactinoma, with subsequent shrinkage of the adenoma but without prolactin normalisation. The patient, a 33-year-old male soccer player with a 5-year history of a macroprolactinoma, was admitted to the hospital with a severe frontal headache, hypotension and muscle stiffness lasting 7 days. Magnetic resonance imaging (MRI) showed obvious pituitary macroprolactinoma (1.8 × 1.8 × 2.0 cm) with azoospermia. He started treatment with cabergoline (0.5 mg thrice a week). 3.5 years later, MRI of the pituitary demonstrated an increase in the adenoma size with haemorrhage, and approximately 8 months later zoospermia was achieved. The patient then affected by pituitary apoplexy coinciding with adenoma shrinkage. Although he continued intake of medication and some symptoms were disappeared, his PRL level did not return to the normal range. He decided to continue cabergoline therapy without surgery. Follow-up was discontinued by the patient.

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UCI(KEPA) : I410-ECN-0101-2020-692-000376958