Poorly differentiated thyroid carcinoma: An institutional experience

Seok Won Choi; Joon-Hyop Lee; Yun Young Kim; Yoo Seung Chung; Sangtae Choi; Na Rae Kim; Jin Mo Kang; Heung Kyu Park; Yong Soon Chun

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자료유형: 학술저널

저자정보: Seok Won Choi (Gachon University Gil Medical Center) Joon-Hyop Lee (Gachon University Gil Medical Center) Yun Young Kim (Gachon University Gil Medical Center) Yoo Seung Chung (Gachon University Gil Medical Center) Sangtae Choi (Gachon University Gil Medical Center) Na Rae Kim (Gachon University College of Medicine) Jin Mo Kang (Gachon University Gil Medical Center) Heung Kyu Park (Gachon University Gil Medical Center) Yong Soon Chun (Gachon University Gil Medical Center)

저널정보: 대한종양외과학회 KOREAN JOURNAL OF CLINICAL ONCOLOGY Korean Journal of Clinical Oncology 제16권 제1호

발행연도: 2020.6

수록면: 25 - 32 (8page)

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Purpose: The incidence of poorly differentiated thyroid carcinoma (PDTC) is extremely low among thyroid cancers and there is no standardized treatment guideline for it. In this study, we have analyzed PDTC patients and reviewed their clinicopathological features.
Methods: Data of PDTC patients from our institution are collected through the electronic medical database. We analyzed them by several parameters such as basic demographics, presenting symptom, preoperative cytology results, associated pathology, surgical results, surgery type, and distant metastasis.
Results: We collected 23 cases in our institution. Apart from two patients who were transferred to another hospital upon diagnosis, all 21 operated cases are analyzed. The parameters we studied were age, sex, presenting symptoms, distant metastasis and pathological features such as tumor size, associated pathology, predominant pattern and so on. We also provided descriptive analyses according to the type of presentation and treatment; patients with distant metastasis, juvenile cancer, and concurrent hyperthyroidism. Furthermore, we provided different cases in which the initial surgical plans differed.
Conclusion: We present 21 cases of PDTC patients and clarify their clinicopathological features. Despite some limitations, this study may shed light for future research regarding treatment of PDTC patients.

#Thyroid neoplasms #Neoplasm metastasis #Surgery

참고문헌 (16)

참고문헌 신청

Sanders EM Jr / 2007 / An evidence-based review of poorly differentiated thyroid cancer / World J Surg 31:934~945

Sakamoto A / 1983 / Poorly differentiated carcinoma of the thyroid : a clinicopathologic entity for a high-risk group of papillary and follicular carcinomas / Cancer 52:1849~1855

Van der Laan BFAM / 1993 / The association of well-differentiated thyroid carcinoma with insular or anaplastic thyroid carcinoma; evidence for dedifferentiation in tumor progression / Endocr Pathol 4:215~221

Asioli S / 2010 / Poorly differentiated carcinoma of the thyroid : validation of the Turin proposal and analysis of IMP3 expression / Mod Pathol 23:1269~1278

Ibrahimpasic T / 2019 / Poorly differentiated carcinoma of the thyroid gland : current status and future prospects / Thyroid 29:311~321

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