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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 86 - 104 (19page)
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Objectives: The purpose of this study is to evaluate efficacy and safety of Mahaenggamsuktang for treating mycoplasma pneumonia in children based on the randomized controlled trials (RCTs). Methods: Literatures were searched from OASIS, KISS, NDSL, CNKI, Cochrane, Embase and Pubmed, and the search was conducted on January 29, 2020. Only RCTs published since 2000 were included. Trials comparing Mahaenggamsuktang combined with antibiotics or antibiotics treatment alone for the treatment of mycoplasma pneumonia in children were included. Results: 17 trials, including 2,241 participants with mycoplasma pneumonia were included in this review. As a result of the meta-analysis, total effective rate of combination of Mahaggamsuktang and antibiotics was 1.24 times higher than that of the antibiotics alone, which was statistically significant. Symptoms with fever, lung sounds, cough, chest X-ray lesion findings, wheezing were also significantly reduced in the treatment group with Mahaenggamseoktang and antibiotics. Also, Serum CRP level was significantly lower with combination treatment. The incidence of adverse reactions was lower in the treatment group with Mahaenggamseoktang and antibiotics, but it was not statistically significant. Conclusions: As a result of meta-analysis, combination treatment of Mahaenggamseoktang and antibiotics seems to have a significantly effective for the treatment of mycoplasma pneumonia in children. In order to have a higher level of evidence for efficacy and safety of Mahaenggamsuktang in treating mycoplasma pneumonia, additional RCTs with good qualities are required.
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참고문헌 (35)
참고문헌 신청
이승현 / 2005 / 마이코플라즈마 폐렴의 임상 역학적 연구(1993-2003년) / Clinical and Experimental Pediatrics 48(2):154~157
남찬희 / 2005 / 소아 마이코플라즈마 폐렴에서 연령별 비교 / Pediatric Infection and Vaccine 12(2):135~139
김은경 / 2015 / Epidemiological comparison of three Mycoplasma pneumoniae pneumonia epidemics in a single hospital over 10 years / Clinical and Experimental Pediatrics 58(5):172~177
You-Sook Youn / 2012 / Mycoplasma pneumoniae pneumonia in children / Clinical and Experimental Pediatrics 55(2):42~47
Ahn HS / 2016 / Hong chang-ui pediatrics / Nuraen Co :700~701
남찬희 / 2005 / 소아 마이코플라즈마 폐렴에서 연령별 비교 / Pediatric Infection and Vaccine 12(2):135~139
김은경 / 2015 / Epidemiological comparison of three Mycoplasma pneumoniae pneumonia epidemics in a single hospital over 10 years / Clinical and Experimental Pediatrics 58(5):172~177
You-Sook Youn / 2012 / Mycoplasma pneumoniae pneumonia in children / Clinical and Experimental Pediatrics 55(2):42~47
Ahn HS / 2016 / Hong chang-ui pediatrics / Nuraen Co :700~701
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