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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 38 - 43 (6page)
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초록· 키워드
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Background: Mycoplasma is a common cause of respiratory infections and may require differential diagnosis from Kawasakidisease (KD). In this study, we investigated the frequency and clinical manifestations of mycoplasma infection in patients withKD.
Materials and Methods: Medical records of 375 in-patients admitted for treatment during the acute stage of KD, were collected,and reviewed retrospectively. Of these patients, 152 (40.5%) were also tested for recent mycoplasma infection. Patients withpositive results (anti-mycoplasma IgM Ab >1:640 or cold agglutinin >1:64) were designated as the case group (n = 37, 24.3%)whereas those with negative results were designated as the control group (n = 115, 75.7%). Clinical findings of the two groupswere compared.
Results: Patients in the case group were older than those in the control group (mean age, 48.2 ± 32.1 months, vs. 31.7 ± 21.7months; P = 0.001). There were significant differences between the case and control groups in the changes in the extremities(78.3% vs. 57.4%, respectively; P = 0.031), and in fever duration (6.5 ± 2.5 days vs. 5.4 ± 1.5 days; P = 0.047). Of the 37 patientswith positive mycoplasma testing, 7 (18.9%) had persistent fever even after the symptoms and signs of systemic inflammation(acute phase of KD) had been resolved. These patients were positive for mycoplasma infection during further evaluation ofpersistent fever, and all of them responded to macrolide antibiotics.
Conclusions: We found that mycoplasma infection is somewhat related to KD. When fever persists after resolution of the acutestage of KD, mycoplasma infection may be considered as a possible cause of fever in preschool-aged children.
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참고문헌 (16)
참고문헌 신청
Atkinson TP / 2008 / Waites KB Epidemiology, clinical manifestations, pathogenesis and laboratory detection of Mycoplasma pneumonia infections / FEMS Microbiol Rev 32 : 956
Chang LY / 2014 / Viral infections associated with Kawasaki disease / J Formos Med Assoc 113 : 148 ~ 154
Chung SW / 2014 / Analysis of genotype distribution and detection rate of Mycoplasma pneumoniae according to respiratory disease type / Public Health Weekly Report 7 : 177 ~
Csango PA / 2004 / Comparison of four Mycoplasma pneumonia IgM-, IgG- and IgA specific enzyme immunoassays in blood donors and patients / Clin Microbiol Infect 10 : 1094 ~ 1
Greco F / 2007 / Cutaneous vasculitis associated with Mycoplasma pneumoniae infection: case report and literature review / Clin Pediatr (Phila) 46 : 451 ~ 453
Chang LY / 2014 / Viral infections associated with Kawasaki disease / J Formos Med Assoc 113 : 148 ~ 154
Chung SW / 2014 / Analysis of genotype distribution and detection rate of Mycoplasma pneumoniae according to respiratory disease type / Public Health Weekly Report 7 : 177 ~
Csango PA / 2004 / Comparison of four Mycoplasma pneumonia IgM-, IgG- and IgA specific enzyme immunoassays in blood donors and patients / Clin Microbiol Infect 10 : 1094 ~ 1
Greco F / 2007 / Cutaneous vasculitis associated with Mycoplasma pneumoniae infection: case report and literature review / Clin Pediatr (Phila) 46 : 451 ~ 453
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