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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 596 - 602 (7page)
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초록· 키워드
오류제보하기
Objective Observations of sex differences have led some scientists to doubt whether the neuroendocrine system is involved in attentiondeficit/hyperactivity disorder (ADHD) etiology. One of the interesting study subjects in this context is prenatal steroid hormone exposure. The aim of the present study was to replicate and extend previous work by addressing two research questions: 1) Are second-tofourth digit (2D:4D) ratios lower in ADHD than in controls? 2) Is there a correlation between 2D:4D ratios and symptoms of ADHD, aggression and intelligence scores in boys with ADHD?Methods The study included 100 treatment-naive male children diagnosed with ADHD and 55 healthy male children. We measured the ratios of 2D:4D and administered a Wechsler Intelligence Scale for Children-Revised to assess IQ scores, as well as behavioral rating scales, in children with ADHD and comparison individuals.Results We observed lower 2D:4D ratios in the right hand in ADHD in comparison to the control group. The left-hand ratios of 2D:4D, however, did not differ between ADHD and control groups. There were negative correlations between the left-hand 2D:4D ratios and the hyperactivity scores. However, no significant correlation was detected between right-hand 2D:4D ratios and the psychological questionnaire scores.Conclusion These results provide further evidence that fetal androgen exposure may contribute to the pathophysiology of ADHD, at least in boys.
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등록된 정보가 없습니다.
참고문헌 (51)
참고문헌 신청
Ercan ES / 2019 / The prevalence of childhood psychopathology in Turkey : a crosssectional multicenter nationwide study(EPICPAT-T) / Nord J Psychiatry 73:132~140
Ramtekkar UP / 2010 / Sex and age differences in attention-deficit/hyperactivity disorder symptoms and diagnoses : implications for DSM-V and ICD-11 / J Am Acad Child Adolesc Psychiatry 49:217~228.e1-e3
Willcutt EG / 2012 / The prevalence of DSM-IV attention-deficit/hyperactivity disorder : a meta-analytic review / Neurotherapeutics 9:490~499
Scassellati C / 2012 / Biomarkers and attention-deficit/hyperactivity disorder : a systematic review and metaanalyses / J Am Acad Child Adolesc Psychiatry 51:1003~1019.e20
Faraone SV / 2015 / Attention-deficit/hyperactivity disorder / Nat Rev Dis Prim 1:15020
Ramtekkar UP / 2010 / Sex and age differences in attention-deficit/hyperactivity disorder symptoms and diagnoses : implications for DSM-V and ICD-11 / J Am Acad Child Adolesc Psychiatry 49:217~228.e1-e3
Willcutt EG / 2012 / The prevalence of DSM-IV attention-deficit/hyperactivity disorder : a meta-analytic review / Neurotherapeutics 9:490~499
Scassellati C / 2012 / Biomarkers and attention-deficit/hyperactivity disorder : a systematic review and metaanalyses / J Am Acad Child Adolesc Psychiatry 51:1003~1019.e20
Faraone SV / 2015 / Attention-deficit/hyperactivity disorder / Nat Rev Dis Prim 1:15020
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