지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 1,026 - 1,034 (9page)
이용수
초록· 키워드
오류제보하기
Objective: This study was conducted to investigate the lipid-lowering effect and safety of Daeshiho-tang in patients with uncontrolled lipid levels by statins. Methods: We investigated patients who had an abnormal lipid profile even when taking statins and who were administered Daeshiho-tang at Kyung-Hee University Korean Medical Hospital for at least one day between January 2008 and December 2018. Their basal characteristics and examinations were reviewed retrospectively with respect to lipid profile, AST, ALT, GGT, BUN, and creatinine. The lipid profile was composed of total cholesterol, triglyceride, LDL-cholesterol, and HDL-cholesterol. Subgroup analysis was performed on each component of dyslipidemia. Results: Among 20 participants, there were 10 males and 10 females. The mean BMI was 23.52. Eighty five percent of the participants were diagnosed as having cerebral infarction. After the administration of Daeshiho-tang, total cholesterol and LDL cholesterol were significantly reduced, to 41.3 mg/dl and 33.95 mg/dl, respectively. In subgroup analyses, total cholesterol and LDL cholesterol were significantly decreased, to 63 mg/dl and 54.6 mg/dl, respectively. Liver and kidney function showed no significant difference after taking Daeshiho-tang. Conclusions: Daeshiho-tang as a decoction or powder had significant lipid-lowering effects on total cholesterol and LDL cholesterol in patients with dyslipidemia. The lipid-lowering effect on total and LDL cholesterol increased in patients with hypercholesterolemia and hyper-LDL-cholesterolemia, respectively. Based on the minimal changes in the liver and kidney function test, Daeshiho-tang would be safe enough to be used in clinics.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
한국지질동맥경화학회진료지침위원회 / 2018 / 이상지질 혈증 치료지침 / 도서출판 아카데미아 :5~28
보건복지부 질병관리본부 / 2017 / 2016국민건강통계 I, 국민건강영양조사 제 7기 1차년도(2016)
이세라 / 2018 / 의약품부작용보고시스템 데이터베이스를 이용한 고강도 statin과 중·저강도 statin 관련 이상사례 비교 분석 / 한국임상약학회지 28(4):293~299
Maningat P / 2013 / How do we improve patient compliance and adherence to long-term statin therapy? / Current Atherosclerosis Reports 15(1):291
이장천 / 2003 / 시호 추출물이 고지방식이를 급여 한 흰쥐의 혈청지질 및 항산화계에 미치는 영향 / 대한한의학방제학회지 11(1):151~159
보건복지부 질병관리본부 / 2017 / 2016국민건강통계 I, 국민건강영양조사 제 7기 1차년도(2016)
이세라 / 2018 / 의약품부작용보고시스템 데이터베이스를 이용한 고강도 statin과 중·저강도 statin 관련 이상사례 비교 분석 / 한국임상약학회지 28(4):293~299
Maningat P / 2013 / How do we improve patient compliance and adherence to long-term statin therapy? / Current Atherosclerosis Reports 15(1):291
이장천 / 2003 / 시호 추출물이 고지방식이를 급여 한 흰쥐의 혈청지질 및 항산화계에 미치는 영향 / 대한한의학방제학회지 11(1):151~159
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Direct LDL Cholesterol Assay vs. Estimated Equations in Patients With Hypertriglyceridemia or Low LDL Cholesterol Levels
Annals of Laboratory Medicine
2024 .07
-
Should We Intensify Statin Management in ACS Patients with Very Low LDL Cholesterol Levels?
지질·동맥경화학회지
2019 .01
-
뇌경색 후 발생한 마비성 장폐색 환자에 보류관장과 대시호탕 병행 치험 1례
대한한방내과학회지
2016 .01
-
Efficacy of Evolocumab in Patients with Hypercholesterolemia
고신대학교 의과대학 학술지
2020 .01
-
Low-Density Lipoprotein Cholesterol Level, Statin Use and Myocardial Infarction Risk in Young Adults
지질·동맥경화학회지
2022 .09
-
Intuitive Modification of the Friedewald Formula for Calculation of LDL-Cholesterol
Annals of Laboratory Medicine
2023 .01
-
Lipid Profile Change after Thyroidectomy
The Journal of Endocrine Surgery
2020 .01
-
Pharmacological Strategies beyond Statins: Ezetimibe and PCSK9 Inhibitors
지질·동맥경화학회지
2019 .01
-
Evaluation of Lipid Profile Changes in Pediatric Patients with Acute Mononucleosis
Infection and Chemotherapy
2017 .01
-
Apolipoprotein B, Non-HDL Cholesterol, and LDL Cholesterol as Markers for Atherosclerotic Cardiovascular Disease Risk Assessment
Annals of Laboratory Medicine
2023 .05
-
Role of Blood Lipid Levels and Lipid-Lowering Therapy in Stroke Patients with Different Levels of Cerebral Artery Diseases: Reconsidering Recent Stroke Guidelines
대한뇌졸중학회지
2021 .01
-
Lipid Management in Korean People with Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
Diabetes and Metabolism Journal
2023 .01
-
Lipid Management in Korean People With Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
지질·동맥경화학회지
2023 .01
-
Association between Low-Density Lipoprotein Cholesterol Level and Cardiovascular Outcomes in Korean Adults: A Nationwide Cohort Study
Diabetes and Metabolism Journal
2023 .01
-
REvisiting Lipids in REtinal Diseases: A Focused Review on Age-related Macular Degeneration and Diabetic Retinopathy
지질·동맥경화학회지
2020 .01
-
Risk of Cardiovascular Disease according to Baseline Low-Density Lipoprotein Cholesterol Level in Different Age Groups in Korean Diabetes Population: A Cohort Study
Diabetes and Metabolism Journal
2024 .03
-
발효옻 추출물이 흰쥐의 식이성 고지혈증에 미치는 영향
동의생리병리학회지
2016 .06
-
발효옻 추출물이 흰쥐의 식이성 고지혈증에 미치는 영향
동의생리병리학회지
2016 .01
-
Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments
Endocrinology and Metabolism
2020 .01
-
Differential Benefit of Statin in Secondary Prevention of Acute Myocardial Infarction according to the Level of Triglyceride and High Density Lipoprotein Cholesterol
Korean Circulation Journal
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0