지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
The emergence of phosphodiesterase (PDE) 5 inhibitors gave rise to the solution for erectile dysfunction, starting with the development of sildenafil. Although their efficacy in treating erectile dysfunction has been shown, the side effects of PDE5 inhibitors, especially sildenafil, must be taken into consideration. A 64-year-old man received 100 mg of sildenafil and experienced blue vision in both eyes; however, after a day or so, his symptoms improved. The symptoms disappeared when he stopped administering sildenafil, but reappeared when the medication was re-administered. Therefore, he discontinued sildenafil treatment and was prescribed udenafil instead. After that, visual adverse events no longer occurred. Causality assessment showed that in this case, sildenafil-induced cyanopsia was “certain” under the World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria and Korean causality assessment algorithm (Ver.2), and was “probable” according to the Naranjo scale. In addition, sildenafil also led to abnormal visual reactions in other cases. Sildenafil can also inhibit PDE6, which is present in retinal cells, unlike other PDE5 inhibitors. Thus, visual adverse reactions, such as blue vision, are the unique results of sildenafil, and other PDE5 inhibitors may be used to prevent them.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Feldman HA / 1994 / Impotence and its medical and psychosocial correlates : results of the Massachusetts Male Aging Study / J Urol 151(1):54~61
Wespes E / 2006 / EAU Guidelines on erectile dysfunction : an update / Eur Urol 49(5):806~815
Huang SA / 2013 / Phosphodiesterase-5 (PDE5) inhibitors In the management of erectile dysfunction / P T 38(7):407~419
Ministry of Food and Drug Safety Integrated Medicine Information System / VIAGRA® Tablets 50 mg/ 100 mg (sildenafil citrate) 2014
Ministry of Food and Drug Safety Integrated Medicine Information System / Cialis 10 mg (tadalafil) 2017
Wespes E / 2006 / EAU Guidelines on erectile dysfunction : an update / Eur Urol 49(5):806~815
Huang SA / 2013 / Phosphodiesterase-5 (PDE5) inhibitors In the management of erectile dysfunction / P T 38(7):407~419
Ministry of Food and Drug Safety Integrated Medicine Information System / VIAGRA® Tablets 50 mg/ 100 mg (sildenafil citrate) 2014
Ministry of Food and Drug Safety Integrated Medicine Information System / Cialis 10 mg (tadalafil) 2017
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Metformin and Sildenafil Attenuate Inflammation and Suppress Apoptosis After Ischemia/Reperfusion Injuries in Rat Urinary Bladder
International Neurourology Journal
2021 .12
-
Sildenafil Ameliorates Advanced Glycation End Products-Induced Mitochondrial Dysfunction in HT-22 Hippocampal Neuronal Cells
대한신경외과학회지
2016 .01
-
Fixed Drug Eruption Caused by Sildenafil Citrate
Annals of Dermatology
2017 .01
-
Comparison of Prostaglandin E1 and Sildenafil Citrate Administration on Skin Flap Survival in Rats
Archives of craniofacial surgery : ACFS
2015 .01
-
Effect of Sildenafil as a treatment for anxious phenotypes in mild ischemic stroke
대한체질인류학회 학술대회 연제 초록
2022 .05
-
경구복용 발기부전치료제의 다양한 임상적 적용
임상노인의학회지
2023 .04
-
Effect of phosphodiesterase type 5 inhibitors on sperm motility and acrosome reaction: An in vitro study
Investigative and Clinical Urology
2021 .01
-
Verification for sildenafil as a potential therapeutic effector following mild ischemic stroke
대한체질인류학회 학술대회 연제 초록
2021 .05
-
Effects of Sildenafil on the recovery of cognitive function following transient global cerebral ischemia in gerbils
대한체질인류학회 학술대회 연제 초록
2024 .05
-
Diffuse Alveolar Hemorrhage Confirmed by Bronchoalveolar Lavage in a Patient with Hemoptysis after Sildenafil Use for Erectile Dysfunction
Acute and Critical Care
2015 .01
-
Prolonged oral sildenafil use-induced Mondor disease: a case report
Journal of Yeungnam Medical Science
2022 .07
-
The effect of two phosphodiesterase inhibitors on bone healing in mandibular fractures (animal study in rats)
대한구강악안면외과학회지
2020 .08
-
Fast Cicatrization of Extensive Livedoid Vasculopathy Ulcers under Treatment with Sildenafil
Annals of Dermatology
2017 .01
-
Phosphodiesterase type 5 inhibitor administered immediately after radical prostatectomy temporarily increases the need for incontinence pads, but improves final continence status
Investigative and Clinical Urology
2016 .01
-
Aggravation of Hepatopulmonary Syndrome after Sildenafil Treatment in a Patient with Coexisting Portopulmonary Hypertension
Korean Circulation Journal
2015 .01
-
Usage and perceptions of phosphodiesterase type 5 inhibitors among the male partners of infertile couples
Clinical and experimental reproductive medicine : CERM
2016 .01
-
A Meta-Analysis of Long- Versus Short-Acting Phosphodiesterase 5 Inhibitors: Comparing Combination Use With α-Blockers and α-Blocker Monotherapy for Lower Urinary Tract Symptoms and Erectile Dysfunction
International Neurourology Journal
2015 .01
-
남성성기능장애의 약물요법
대한의사협회지
2020 .01
-
Development of a Pde6b gene knockout rat model for studies of degenerative retinal diseases
한국실험동물학회 학술발표대회 논문집
2020 .02
-
국내 남성에서 포스포디에스테라제 5형 억제제 불법유통 사용현황, 안전성및 관련 요인
한국임상약학회지
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0