지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Several studies about bee venom components have reported anti-fungal, anti-inflammatory, and anti-cancer effects. Malassezia species are components of skin flora, and also associated with many dermatologic diseases such as seborrheic dermatitis, pityriasis versicolor, folliculitis, and atopic dermatitis. Objective: To investigate the antifungal activity of bee venom components, melittin, and apamin, against Malassezia strains. Methods: With 10 Malassezia species, minimal inhibitory concentrations (MICs) were tested with bee venom, and Zinc pyrithione as a reference antifungal agent. Results: Whole bee venom, melittin, and apamin did not show any antifungal activity against Malassezia species at the concentrations tested. Conclusion: Although bee venom do not have anti-Malassezia activities, it is known to have antifungal activities against other fungal strains. Therefore, further study should consider revealing the mechanism of antifungal activity against fungus and other possible target strains of fungi.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Prohic A / 2016 / Malassezia species in healthy skin and in dermatological conditions / Int J Dermatol 55:494~504
Saunders CW / 2012 / Malassezia fungi are specialized to live on skin and associated with dadruff, eczema, and other skin diseases / PLoS Pathog 8:e1002701
Park M / 2018 / Understanding the mechanism of action of the anti-dandruff agent zinc pyrithione against Malassezia restricta / Sci Rep 8:12086
White TC / 2014 / Fungi on the skin: dermatophytes and Malassezia / Cold Spring Harb Perspect Med 4
An HJ / 2018 / Therapeutic effects of bee venom and its major component, melittin, on atopic dermatitis in vivo and in vitro / Br J Pharmacol 175:4310~4324
Saunders CW / 2012 / Malassezia fungi are specialized to live on skin and associated with dadruff, eczema, and other skin diseases / PLoS Pathog 8:e1002701
Park M / 2018 / Understanding the mechanism of action of the anti-dandruff agent zinc pyrithione against Malassezia restricta / Sci Rep 8:12086
White TC / 2014 / Fungi on the skin: dermatophytes and Malassezia / Cold Spring Harb Perspect Med 4
An HJ / 2018 / Therapeutic effects of bee venom and its major component, melittin, on atopic dermatitis in vivo and in vitro / Br J Pharmacol 175:4310~4324
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