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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제13권 제2호
- 발행연도
- 2020.1
- 수록면
- 186 - 193 (8page)
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Objectives. This study was conducted to compare clinicopathologic and radiologic factors between benign and malignant thyroid nodules and to evaluate the diagnostic performance of shear wave elastography (SWE) combined with B-mode ultrasonography (US) in differentiating malignant from benign thyroid nodules. Methods. This retrospective study included 92 consecutive patients with 95 thyroid nodules examined on B-mode US and SWE before US-guided fine-needle aspiration biopsy or surgical excision. B-mode US findings (composition, echogenicity, margin, shape, and calcification) and SWE elasticity parameters (maximum [Emax], mean, minimum, and nodule-to-normal parenchymal ratio of elasticity) were reviewed and compared between benign and malignant thyroid nodules. The diagnostic performance of B-mode US and SWE for predicting malignant thyroid nodules was analyzed. The optimal cutoff values of elasticity parameters for identifying malignancy were determined. Diagnostic performance was compared between B-mode US only, SWE only, and the combination of B-mode US with SWE. Results. On multivariate logistic regression analysis, age (odds ratio [OR], 0.90; P=0.028), a taller-than-wide shape (OR, 11.3; P=0.040), the presence of calcifications (OR, 15.0; P=0.021), and Emax (OR, 1.22; P=0.021) were independent predictors of malignancy in thyroid nodules. The combined use of B-mode US findings and SWE yielded improvements in sensitivity, the positive predictive value, the negative predictive value, and accuracy compared with the use of B-mode US findings only, but with no statistical significance. Conclusion. When SWE was combined with B-mode US, the diagnostic performance was better than when only B-mode US was used, although the difference was not statistically significant.
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참고문헌 (28)
참고문헌 신청
Kim EK / 2002 / New sonographic criteria for recommending fine-needle aspiration biopsy of nonpalpable solid nodules of the thyroid / AJR Am J Roentgenol 178(3):687~691
하은주 / 2016 / A Multicenter Prospective Validation Study for the Korean Thyroid Imaging Reporting and Data System in Patients with Thyroid Nodules / Korean Journal of Radiology 17(5):811~821
Hoang JK / 2007 / US Features of thyroid malignancy : pearls and pitfalls / Radiographics 27(3):847~860
Iannuccilli JD / 2004 / Risk for malignancy of thyroid nodules as assessed by sonographic criteria : the need for biopsy / J Ultrasound Med 23(11):1455~1464
Alexander EK / 2008 / Approach to the patient with a cytologically indeterminate thyroid nodule / J Clin Endocrinol Metab 93(11):4175~4182
하은주 / 2016 / A Multicenter Prospective Validation Study for the Korean Thyroid Imaging Reporting and Data System in Patients with Thyroid Nodules / Korean Journal of Radiology 17(5):811~821
Hoang JK / 2007 / US Features of thyroid malignancy : pearls and pitfalls / Radiographics 27(3):847~860
Iannuccilli JD / 2004 / Risk for malignancy of thyroid nodules as assessed by sonographic criteria : the need for biopsy / J Ultrasound Med 23(11):1455~1464
Alexander EK / 2008 / Approach to the patient with a cytologically indeterminate thyroid nodule / J Clin Endocrinol Metab 93(11):4175~4182
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