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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 51 - 57 (7page)
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Purpose: Although increasing body mass index (BMI) is regarded as a potential risk factor for breast cancer (BC) in postmenopausal women, research on premenopausal women has produced conflicting results. We investigated the association between BMI and BC according to menopausal status in Korean. Methods: We analyzed clinical data from 186,835 women aged 20 years or older between 2003 and 2008 using a sample cohort from the national database in Korea. We identified women newly diagnosed with BC and estimated the risk of BC according to BMI (kg/m2). Subjects were categorized into five groups according to World Health Organization recommendations for Asians: underweight, <18.5 kg/m2; normal weight, 18.5–22.9 kg/m2; overweight, 23.0–24.9 kg/m2; obese class I, 25.0–29.9 kg/m2; and obese class II, ≥30.0 kg/m2. Results: 1,372 women in the cohort were newly diagnosed with BC. A positive relationship between BMI and BC was detected and the hazard ratio in each group compared with the normal weight group was 0.57 (95% CI, 0.42–0.78), 1.27 (1.11–1.45), 1.25 (1.09–1.44), and 1.28 (0.95–1.73), respectively. BMI was determined to be an important risk factor for BC in postmenopausal women (p for trend was 0.015). We failed to find a significant correlation between BMI and BC in premenopausal women. Conclusion: BMI is positively associated with BC in postmenopausal Korean women.
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