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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Human scalp hair is composed of bio-synthesized protein that stores and excretes excess elements from the body. Thus, the concentration of major and trace elements in the hair may provide insight into both the physiology and health status of humans. Monitoring of health status by hair analysis is limited by the uncertainty surrounding natural changes in composition based on age and sex parameters. Methods: A total of 322 hair samples from subjects aged 0–89 years were collected and analyzed to determine their sulfur, calcium, magnesium, zinc, and copper concentrations by inductively coupled plasma mass spectrometry. The age- and sex-dependence of the concentrations of these elements within scalp hair was evaluated. Age-dependence was analyzed by least squares fitting of the data from young people (up to 25 years old). Sex-dependence was evaluated by comparing the average element concentrations of males and females in each age groups. Results: The concentration of mineral elements increased with age up to 25 years old. Calcium and magnesium contents were strongly affected by age, whereas the effects were weaker for zinc and copper. In participants over 20 years old, sex and the concentrations of calcium and magnesium were significantly associated. The concentrations of these elements were higher in most of the subgroups of adult women. The concentrations of sulfur, zinc, and copper were not significantly associated with age or sex. Conclusions: The concentrations of major inorganic elements in scalp hair showed an increasing trend up to 25 years of age, and a strong sex dependence of calcium and magnesium concentrations in the subjects older than 20 years. More research is needed to understand the physiology of calcium and magnesium excretion though scalp hair.
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참고문헌 (17)
참고문헌 신청
Akarsh Verma / 2016 / Human Hair: A Biodegradable Composite Fiber–A Review / International Journal of Waste Resources 6(2)
Popescu C / 2007 / Hair-the most sophisticated biological composite material / Chem Soc Rev 36:1282~1291
Mahdavi-Roshan M / 2015 / Copper, magnesium, zinc and calcium status in osteopenic and osteoporotic post-menopausal women / Clin Cases Miner Bone Metab 12(1):18~21
Miekeley N / 2001 / Elemental anomalies in hair as indicators of endocrinologic pathologies and deficiencies in calcium and bone metabolism / J Trace Elem Med Biol 15:46~55
MacPherson A / 2000 / Relationship of hair calcium concentration to incidence of coronary heart disease / Sci Total Environ 255:11~19
Popescu C / 2007 / Hair-the most sophisticated biological composite material / Chem Soc Rev 36:1282~1291
Mahdavi-Roshan M / 2015 / Copper, magnesium, zinc and calcium status in osteopenic and osteoporotic post-menopausal women / Clin Cases Miner Bone Metab 12(1):18~21
Miekeley N / 2001 / Elemental anomalies in hair as indicators of endocrinologic pathologies and deficiencies in calcium and bone metabolism / J Trace Elem Med Biol 15:46~55
MacPherson A / 2000 / Relationship of hair calcium concentration to incidence of coronary heart disease / Sci Total Environ 255:11~19
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