지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 592 - 596 (5page)
이용수
초록· 키워드
오류제보하기
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious zoonosis caused by the SFTS virus. Hemophagocyticlymphohistiocytosis (HLH) is a life-threatening syndrome associated with excessive immune activation. Cytokine stormsare often seen in both SFTS and HLH, resulting in rapid disease progression and poor prognosis. The aim of this study was toidentify whether SFTS cases complicated by HLH are related to higher rates of mortality. Descriptive analysis of the frequency ofclinical and laboratory data, complications, treatment outcomes, and HLH-2004 criteria was performed. Cases presenting withfive or more clinical or laboratory findings corresponding to the HLH-2004 diagnostic criteria were defined as SFTS cases complicatedby HLH. Eighteen cases of SFTS were identified during a 2-year study period, with a case-fatality proportion of 22.2% (4among 18 cases, 95% confidence interval 9%–45.2%). SFTS cases complicated by HLH were identified in 33.3% (6 among 18 cases). A mortality rate of 75% (3 among 4 cases) was recorded among SFTS cases complicated by HLH. Although there were no statisticallysignificant differences in outcomes, fatal cases exhibited more frequent correlation with HLH-2004 criteria than non-fatalcases [3/14 (21.4%) vs. 3/4 (75%), p=0.083]. In conclusion, the present study suggests the possibility that SFTS casescomplicated by HLH are at higher risk of poor prognosis.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
International Committee on Taxonomy of Viruses (ICTV) / Taxonomy
Liu Q / 2014 / Severe fever with thrombocytopenia syndrome, an emerging tick-borne zoonosis / Lancet Infect Dis 14:763~772
Li H / 2018 / Epidemiological and clinical features of laboratory-diagnosed severe fever with thrombocytopenia syndrome in China, 2011-17 : a prospective observational study / Lancet Infect Dis 18:1127~1137
Kaneko M / 2015 / A fatal case of severe fever with thrombocytopenia syndrome complicated by hemophagocytic lymphohistiocytosis / Kansenshogaku zasshi 89:592~596
Oh HS / 2016 / Hemophagocytic lymphohistiocytosis associated with SFTS virus infection: a case report with literature review / Medicine (Baltimore) 95:e4476
Liu Q / 2014 / Severe fever with thrombocytopenia syndrome, an emerging tick-borne zoonosis / Lancet Infect Dis 14:763~772
Li H / 2018 / Epidemiological and clinical features of laboratory-diagnosed severe fever with thrombocytopenia syndrome in China, 2011-17 : a prospective observational study / Lancet Infect Dis 18:1127~1137
Kaneko M / 2015 / A fatal case of severe fever with thrombocytopenia syndrome complicated by hemophagocytic lymphohistiocytosis / Kansenshogaku zasshi 89:592~596
Oh HS / 2016 / Hemophagocytic lymphohistiocytosis associated with SFTS virus infection: a case report with literature review / Medicine (Baltimore) 95:e4476
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Severe Fever with Thrombocytopenia Syndrome Presenting with Hemophagocytic Lymphohistiocytosis
Infection and Chemotherapy
2016 .12
-
Severe Fever with Thrombocytopenia Syndrome Patients with Hemophagocytic Lymphohistiocytosis Retrospectively Identified in Korea, 2008–2013
Journal of Korean Medical Science
2018 .01
-
혈구탐식성 림프조직구증이 동반된 중증열성혈소판감소증후군 1예
대한내과학회지
2016 .01
-
Current status of the diagnosis and treatment of hemophagocytic lymphohistiocytosis in adults
Blood Research
2021 .01
-
Current status of the diagnosis and treatment of hemophagocytic lymphohistiocytosis in adults
Blood Research
2021 .04
-
A retrospective analysis of etiology and outcomes of hemophagocytic lymphohistiocytosis in children and adults
Journal of Yeungnam Medical Science
2021 .01
-
Hemophagocytic lymphohistiocytosis diagnosed by brain biopsy
Clinical and Experimental Pediatrics
2015 .01
-
The First Case of Non-retrospective Clinical Identification of Severe Fever with Thrombocytopenia Syndrome Patient in 2013 in South Korea
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2015 .06
-
Hemophagocytic Lymphohistiocytosis after Lung Transplantation
Acute and Critical Care
2015 .01
-
Epidemiological and Clinical Characteristics of Confirmed Cases of Severe Fever With Thrombocytopenia Syndrome in Jeju Province, Korea, 2014-2018
예방의학회지
2019 .01
-
Bone Marrow Suppression and Hemophagocytic Histiocytes Are Common Findings in Korean Severe Fever with Thrombocytopenia Syndrome Patients
Yonsei Medical Journal
2016 .01
-
Severe Fever with Thrombocytopenia Syndrome Presenting with Rhabdomyolysis
Infection and Chemotherapy
2017 .01
-
중증열성혈소판감소증후군(SFTS) 환자에 대한 고찰: 현재까지 연구된 치료법을 중점으로
대한수혈학회지
2018 .01
-
A Pediatric Case of Severe Fever with Thrombocytopenia Syndrome in Korea
Journal of Korean Medical Science
2017 .01
-
Hemophagocytic lymphohistiocytosis with recurrent Kikuchi-Fujimoto disease
Journal of Yeungnam Medical Science
2021 .01
-
성인 혈구탐식성림프조직구증식증의 이해, 진단 및 치료
대한내과학회지
2015 .01
-
Confirmed cases of severe fever with thrombocytopenia syndrome in companion cats with a history of tick exposure in the Republic of Korea
Journal of Veterinary Science
2022 .11
-
중증 열성혈소판감소증후군 환자에서 혈장교환술 치료 중 발생한 치명적 폐손상
대한내과학회지
2020 .06
-
Dental management of a patient with hemophagocytic lymphohistiocytosis under general anesthesia: A case report
International Journal of Disability and Oral Health
2022 .12
-
조절되지 않는 열과 발진으로 방문한 환자에서 엡스타인-바바이러스 감염으로 유발된 적혈구포식성림프조직구증식증 1례
대한소아응급의학회지
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0