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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 774 - 781 (8page)
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초록· 키워드
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Purpose: Cerebral small vessel disease (SVD) is known to be associated with ischemic stroke, intracerebral hemorrhage (ICH), andcognitive impairment. In this retrospective observational study, we explored SVD markers on MRI relevant to spontaneous ICH. Materials and Methods: The ICH group consisted of 150 consecutive patients with a first primary parenchymal ICH, and the controlgroup consisted of 271 age- and sex-matched individuals who underwent brain MRI in a health care center. We compared cerebralmicrobleeds (CMBs), white matter hyperintensities (WMHs), enlarged perivascular space (EPVS), and lacunae in the ICHand control groups. Results: A total of 1278 CMB lesions were identified in 121 of the 150 patients in the ICH group (80.6%), while 77 CMB lesions werefound in 32 of the 271 individuals in the control group (11.8%). WMH and EPVS were more severe and lacunae were more frequentin the ICH patients than in the control group. When receiver operating characteristic (ROC) curves were plotted, number of CMBsmost significantly predicted ICH. All imaging markers were significantly associated with ICH in every age group. The location ofCMBs coincided with the location of ICH, and ICH volume correlated with CMB count. Conclusion: All MRI markers for SVD were worse in ICH patients than in healthy controls, and these markers were prominenteven in young ICH patients. Lacunae, WMH, EPVS, and CMB should be considered as factors related with spontaneous ICH.
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참고문헌 (40)
참고문헌 신청
Broderick J / 2007 / Guidelines for the management of spontaneous intracerebral hemorrhage in adults : 2007 update : a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group / Stroke 38:2001~2023
Bogousslavsky J / 1988 / The Lausanne Stroke Registry : analysis of 1, 000 consecutive patients with first stroke / Stroke 19:1083~1092
Broderick JP / 1993 / Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality / Stroke 24:987~993
Fogelholm R / 2005 / Long term survival after primary intracerebral haemorrhage : a retrospective population based study / J Neurol Neurosurg Psychiatry 76:1534~1538
van Asch CJ / 2010 / Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin : a systematic review and meta-analysis / Lancet Neurol 9:167~176
Bogousslavsky J / 1988 / The Lausanne Stroke Registry : analysis of 1, 000 consecutive patients with first stroke / Stroke 19:1083~1092
Broderick JP / 1993 / Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality / Stroke 24:987~993
Fogelholm R / 2005 / Long term survival after primary intracerebral haemorrhage : a retrospective population based study / J Neurol Neurosurg Psychiatry 76:1534~1538
van Asch CJ / 2010 / Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin : a systematic review and meta-analysis / Lancet Neurol 9:167~176
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