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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 579 - 586 (8page)
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Purpose: The impact of changes in body mass index and waist circumference on the development of metachronous colorectal neoplasia (CRN) after polypectomy has rarely been examined. We evaluated the association between changes in overall/abdominal obesity and metachronous CRN risk. Materials and Methods: We studied patients who underwent ≥1 adenoma removal and surveillance colonoscopy. Patients were classified into the following four groups based on the changes in overall obesity from index to follow-up colonoscopy: non-obesity persisted (group 1), obesity to non-obesity (group 2), non-obesity to obesity (group 3), and obesity persisted (group 4). Patients were also divided into another four groups based on similar changes in abdominal obesity (groups 5–8). Results: The number of patients in groups 1, 2, 3, and 4 was 5074, 457, 643, and 3538, respectively, and that in groups 5, 6, 7, and 8 was 4229, 538, 656, and 2189, respectively. Group 4 had a significantly higher risk of metachronous CRN compared to groups 1 and 2. However, metachronous advanced CRN (ACRN) risk was not different among groups 1, 2, 3, and 4. Metachronous CRN risk in group 8 (abdominal obesity persisted) was higher than that in groups 5 (non-abdominal obesity persisted) and 7 (non-abdominal obesity to abdominal obesity), and tended to be higher than that in group 6 (abdominal obesity to non-abdominal obesity). Additionally, group 8 had a significantly higher risk of metachronous ACRN compared to groups 5, 6, and 7. Conclusion: Changes in obesity affected the metachronous CRN risk. In particular, changes in abdominal obesity affected the metachronous ACRN risk.
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참고문헌 (24)
참고문헌 신청
Ma Y / 2013 / Obesity and risk of colorectal cancer : a systematic review of prospective studies / PLoS One 8:e53916
Okabayashi K / 2012 / Body mass index category as a risk factor for colorectal adenomas : a systematic review and meta-analysis / Am J Gastroenterol 107:1175~1185
Lu Y / 2016 / Anthropometry-based obesity phenotypes and risk of colorectal adenocarcinoma : a large prospective cohort study in Norway / Epidemiology 27:423~432
Li H / 2013 / Body weight, fat distribution and colorectal cancer risk: a report from cohort studies of 134255 Chinese men and women / Int J Obes(Lond) 37:783~789
Song M / 2016 / Long-term status and change of body fat distribution, and risk of colorectal cancer : a prospective cohort study / Int J Epidemiol 45:871~883
Okabayashi K / 2012 / Body mass index category as a risk factor for colorectal adenomas : a systematic review and meta-analysis / Am J Gastroenterol 107:1175~1185
Lu Y / 2016 / Anthropometry-based obesity phenotypes and risk of colorectal adenocarcinoma : a large prospective cohort study in Norway / Epidemiology 27:423~432
Li H / 2013 / Body weight, fat distribution and colorectal cancer risk: a report from cohort studies of 134255 Chinese men and women / Int J Obes(Lond) 37:783~789
Song M / 2016 / Long-term status and change of body fat distribution, and risk of colorectal cancer : a prospective cohort study / Int J Epidemiol 45:871~883
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