지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background: Bone marrow oedema (BMO) in children/adolescents is a rare clinical condition without an etiologic cause. It is associated with typical increased signal intensity on T2-weighted magnetic resonance images (MRI) and an increase in bone turnover in which vitamin D plays a pivotal role. No treatment guidelines for these young patients are to date available. Methods: We performed a retrospective study in a pediatric setting of 13 patients with diagnosis of primary BMO of the foot on the basis of clinical and radiological findings. Data collection included sex, age, patient history, symptoms at presentation, clinical examination, laboratory bone turnover markers, vitamin D levels, MRI, treatment, and outcome. Results: Vitamin D deficiency or insufficiency was found in 76.9% of cases. All patients were treated with adequate vitamin D daily intake, a short course of analgesic therapy, physical therapy, avoiding detrimental feet and ankle immobilization. All fully recovered in 3-month lag period. Conclusions: Our data highlight that environmental factors, such as underestimated articular or bone microtraumatisms, as well as joint hyper mobility, in a bone turnover milieu of vitamin D deficiency could be the cause of this clinical conditions. Adequate vitamin D supplementation, associated with physical and analgesic therapy, is crucial in the management of BMO.
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참고문헌 (29)
참고문헌 신청
Horas K / 2017 / High prevalence of vitamin D deficiency in patients with bone marrow edema syndrome of the foot and ankle / Foot Ankle Int 38:760~766
Mirghasemi SA / 2016 / Bone marrow edema syndrome in the foot and ankle / Foot Ankle Int 37:1364~1373
Patel S / 2014 / Primary bone marrow oedema syndromes / Rheumatology (Oxford) 53:785~792
Kröger L / 2004 / Transient bone marrow oedema in a child / Ann Rheum Dis 63:1528~1529
Korompilias AV / 2009 / Bone marrow edema syndrome / Skeletal Radiol 38:425~436
Mirghasemi SA / 2016 / Bone marrow edema syndrome in the foot and ankle / Foot Ankle Int 37:1364~1373
Patel S / 2014 / Primary bone marrow oedema syndromes / Rheumatology (Oxford) 53:785~792
Kröger L / 2004 / Transient bone marrow oedema in a child / Ann Rheum Dis 63:1528~1529
Korompilias AV / 2009 / Bone marrow edema syndrome / Skeletal Radiol 38:425~436
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